# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3579719 | B | Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay | Homo sapiens | 52 | cell-based format | Scientific Literature | ||
2. | ALA3579720 | B | Agonist activity at P2Y10 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay | Homo sapiens | 52 | cell-based format | Scientific Literature | ||
3. | ALA3579721 | B | Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay | Homo sapiens | 52 | cell-based format | Scientific Literature | ||
4. | ALA3579722 | B | Agonist activity at mouse P2Y10 receptor expressed in McA-RH7777 cells assessed as actin stress fiber formation at 1 uM after 30 mins by confocal microscopy | Mus musculus | 4 | cell-based format | Scientific Literature | ||
5. | ALA3816043 | B | Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalpha shedding assay | Mus musculus | 36 | cell-based format | Scientific Literature | ||
6. | ALA3816044 | B | Agonist activity at mouse P2Y10 receptor expressed in HEK293A cells after 1.5 hrs by alkaline phosphatase tagged-TGFalpha shedding assay | Mus musculus | 36 | cell-based format | Scientific Literature | ||
7. | ALA3816045 | B | Intrinsic activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalpha shedding assay relative to O-(Hydroxy(((2R,3R)-2-(((3-(2-((3-phenoxybenzyl)oxy)phenyl)-propanoyl)oxy)methyl)tetrahydro-2H-pyran-3-yl)oxy)phosphoryl)-L-serine | Mus musculus | 35 | cell-based format | Scientific Literature | ||
8. | ALA3816046 | B | Intrinsic activity at mouse P2Y10 receptor expressed in HEK293A cells after 1.5 hrs by alkaline phosphatase tagged-TGFalpha shedding assay relative to diF-C3-ph-o-O-C11 | Mus musculus | 36 | cell-based format | Scientific Literature | ||
9. | ALA3816049 | B | Agonist activity at mouse P2Y10 receptor expressed in rat McA-RH7777 cells assessed as induction of actin stress fiber formation at 100 nM after 30 mins by Alexa fluor 594-labelled phalloidin/DAPI staining based fluorescence microscopy | Mus musculus | 8 | cell-based format | Scientific Literature | ||
10. | ALA4014236 | B | Agonist activity at mouse GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/chimeric Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr | Mus musculus | 36 | cell-based format | Scientific Literature | ||
11. | ALA4014237 | B | Intrinsic activity at mouse GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/chimeric Galphaq/iL assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr relative to O-(Hydroxy(((2R,3R)-2-(((3-(2-((3-phenoxybenzyl)oxy)phenyl)- propanoyl)oxy)methyl)tetrahydro-2H-pyran-3-yl)oxy)phosphoryl)- L-serine | Mus musculus | 30 | cell-based format | Scientific Literature | ||
12. | ALA4014238 | B | Agonist activity at human GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/chimeric Galphaq/i1 assessed as induction of AP-TGFalpha release after 1 hr | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
13. | ALA4014239 | B | Intrinsic activity at human GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/chimeric Galphaq/i1 assessed as induction of AP-TGFalpha release after 1 hr relative to O-(Hydroxy(((2R,3R)-2-(((3-(2-((3-phenoxybenzyl)oxy)phenyl)- propanoyl)oxy)methyl)tetrahydro-2H-pyran-3-yl)oxy)phosphoryl)- L-serine | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
14. | ALA4014240 | B | Agonist activity at mouse GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/chimeric Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr relative to control | Mus musculus | 30 | cell-based format | Scientific Literature | ||
15. | ALA4014241 | B | Agonist activity at human GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/chimeric Galphaq/i1 assessed as induction of AP-TGFalpha release after 1 hr relative to control | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
16. | ALA4729127 | B | Agonist activity at mouse GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr by p-NPP substrate based microplate reader analysis | Mus musculus | 30 | cell-based format | Scientific Literature | ||
17. | ALA4729128 | B | Agonist activity at mouse GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr by p-NPP substrate based microplate reader analysis relative to control | Mus musculus | 30 | cell-based format | Scientific Literature | ||
18. | ALA4729129 | B | Agonist activity at mouse GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr by p-NPP substrate based microplate reader analysis relative to positive control | Mus musculus | 30 | cell-based format | Scientific Literature | ||
19. | ALA4729130 | B | Agonist activity at mouse P2Y10 expressed in HEK293 cells co-transfected with AP-TGFalpha/Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr by p-NPP substrate based microplate reader analysis | Mus musculus | 30 | cell-based format | Scientific Literature | ||
20. | ALA4729131 | B | Agonist activity at mouse P2Y10 expressed in HEK293 cells co-transfected with AP-TGFalpha/Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr by p-NPP substrate based microplate reader analysis relative to control | Mus musculus | 30 | cell-based format | Scientific Literature |