| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA751805 | F | The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 2 (P2X2) receptor 10 uM | Rattus norvegicus | 1 | ALA1135773 | assay format | Scientific Literature | |
| 2. | ALA751808 | F | The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 3 (P2X3 ) | 2 | ALA1135773 | assay format | Scientific Literature | ||
| 3. | ALA754874 | F | Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytes | Rattus norvegicus | 11 | ALA1134335 | cell-based format | Scientific Literature | |
| 4. | ALA754947 | F | Inhibition of inward ion current elicited by ATP at P2X2 receptor expressed in Xenopus oocytes | Rattus norvegicus | 10 | ALA1134335 | cell-based format | Scientific Literature | |
| 5. | ALA751122 | F | Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytes | Rattus norvegicus | 11 | ALA1134335 | cell-based format | Scientific Literature | |
| 6. | ALA872764 | F | Inhibition of ATP-induced K+ efflux (with cations) in adherent HEK293 cells expressing human P2X7 receptor | Homo sapiens | 1 | ALA1134335 | cell-based format | Scientific Literature | |
| 7. | ALA751762 | F | Percentage inhibition of ATP-induced K+ efflux (cation free) in adherent HEK293 cells expressing human P2X7 receptor | Homo sapiens | 9 | ALA1134335 | cell-based format | Scientific Literature | |
| 8. | ALA751763 | F | Percent inhibition of ATP-induced K+ efflux (ethidium influx) in suspended HEK293 cells expressing human P2X7 receptor | Homo sapiens | 10 | ALA1134335 | cell-based format | Scientific Literature | |
| 9. | ALA884926 | F | Inhibition of 10 nM 2-MeS-ADP-stimulated phospholipase C in turkey erythrocyte membranes using [3H]inositol | Meleagris gallopavo | 10 | ALA1134335 | cell membrane format | Scientific Literature | |
| 10. | ALA759513 | F | The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1) | 5 | ALA1135773 | assay format | Scientific Literature | ||
| 11. | ALA856215 | B | Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X1 receptor expressed in Xenopus oocytes. | 3 | ALA1131253 | cell-based format | Scientific Literature | ||
| 12. | ALA766585 | B | Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X3 receptor expressed in Xenopus oocytes. | 3 | ALA1131253 | cell-based format | Scientific Literature | ||
| 13. | ALA895692 | F | Antagonist activity at mouse recombinant P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current at 100 uM by two electrode voltage clamping technique | Mus musculus | 1 | ALA1148747 | cell-based format | Scientific Literature | |
| 14. | ALA895693 | F | Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current at 100 uM by two electrode voltage clamping technique | Homo sapiens | 12 | ALA1148747 | cell-based format | Scientific Literature | |
| 15. | ALA895695 | F | Antagonist activity at human recombinant P2X7 receptor expressed in HEK293 cells assessed as BzATP-induced ethidium accumulation at 10 uM | Homo sapiens | 19 | ALA1148747 | cell-based format | Scientific Literature | |
| 16. | ALA895696 | F | Antagonist activity at human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current by two electrode voltage clamping technique | Homo sapiens | 5 | ALA1148747 | cell-based format | Scientific Literature | |
| 17. | ALA2379687 | B | Selectivity ratio of IC50 for mouse recombinant P2X1 receptor to IC50 for human recombinant P2X3 receptor | 3 | ALA2375299 | assay format | Scientific Literature | ||
| 18. | ALA2379689 | B | Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current incubated for 20 mins prior to ATP-induction by two-electrode voltage clamp assay | Homo sapiens | 3 | ALA2375299 | cell-based format | Scientific Literature | |
| 19. | ALA2379815 | B | Antagonist activity at mouse recombinant P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current incubated for 20 mins prior to ATP-induction by two-electrode voltage clamp assay | Mus musculus | 3 | ALA2375299 | cell-based format | Scientific Literature | |
| 20. | ALA2379816 | B | Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current at 100 nM incubated for 20 mins prior to ATP-induction by two-electrode voltage clamp assay | Homo sapiens | 7 | ALA2375299 | cell-based format | Scientific Literature |
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