# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA616427 | Binding | Binding affinity against 5-hydroxytryptamine 1A receptor from rat hippocampus using [3H]8-OH-DPAT as the radioligand. | 2 | ALA1131235 | tissue-based format | Scientific Literature | ||
2. | ALA616763 | Binding | Binding affinity against 5-hydroxytryptamine 1B receptor in membranes of Rat cerebral cortex | 8 | ALA1131235 | tissue-based format | Scientific Literature | ||
3. | ALA616811 | Binding | Binding affinity against 5-hydroxytryptamine 1B receptor - 5-hydroxytryptamine 1D receptor using [3H]5-HT as the radioligand. | 2 | ALA1131235 | protein format | Scientific Literature | ||
4. | ALA621539 | Binding | Binding affinity against 5-hydroxytryptamine 2A receptor from rat cortex using [3H]ketanserin as the radioligand. | 2 | ALA1131235 | assay format | Scientific Literature | ||
5. | ALA621509 | Binding | Binding affinity against 5-hydroxytryptamine 2C receptor from rat cortex using [3H]mesulergine as the radioligand. | 2 | ALA1131235 | tissue-based format | Scientific Literature | ||
6. | ALA620792 | Binding | Binding affinity against 5-hydroxytryptamine 6 receptor from CHO cell membranes using [3H]5-HT as the radioligand. | 1 | ALA1131235 | cell-based format | Scientific Literature | ||
7. | ALA872929 | Binding | Binding affinity against 5-hydroxytryptamine 7 receptor using from CHO cell membranes [3H]5-HT as the radioligand. | 1 | ALA1131235 | cell-based format | Scientific Literature | ||
8. | ALA647661 | Binding | Binding affinity against Alpha-2 adrenergic receptor in rat cortex using [3H]RX-821002 as the radioligand. | 2 | ALA1131235 | tissue-based format | Scientific Literature | ||
9. | ALA646867 | Binding | Binding affinity against Alpha-1 adrenergic receptor in rat cortex using [3H]prazosin as the radioligand. | 2 | ALA1131235 | tissue-based format | Scientific Literature | ||
10. | ALA648650 | Binding | Binding affinity against Beta adrenergic receptor in rat cortex using [3H]dihydroalprenolol as the radioligand. | 2 | ALA1131235 | assay format | Scientific Literature | ||
11. | ALA652460 | Functional | Antagonism of the induced potentiation of K+ stimulated [3H]5-HT release from brain slices with 5-HT (1000 nM) at a concentration of 1000nM, expressed as percent of control | Rattus norvegicus | 1 | ALA1131235 | tissue-based format | Scientific Literature | |
12. | ALA655245 | Functional | Antagonism of the induced potentiation of K+ stimulated [3H]-5-HT release from brain slices with 5-HT (100 nM) at a concentration of 1000 nM, expressed as percent of control | Rattus norvegicus | 1 | ALA1131235 | tissue-based format | Scientific Literature | |
13. | ALA655246 | Functional | Potentiation of K+ stimulated release of [3H]5-HT from brain slices at a concentration of 0 nM. (activity expressed as ratio of S2 (second stimulation)/S1(first stimulation)) | Rattus norvegicus | 1 | ALA1131235 | tissue-based format | Scientific Literature | |
14. | ALA655247 | Functional | Potentiation of K+ stimulated release of [3H]5-HT from brain slices at a concentration of 1000 nM. (activity expressed as ratio of S2 (second stimulation)/S1(first stimulation)) | Rattus norvegicus | 1 | ALA1131235 | tissue-based format | Scientific Literature | |
15. | ALA655248 | Functional | Potentiation of K+ stimulated release of [3H]5-HT from brain slices at a concentration of 100 nM. (activity expressed as ratio of S2 (second stimulation)/S1(first stimulation)) | Rattus norvegicus | 1 | ALA1131235 | tissue-based format | Scientific Literature | |
16. | ALA651423 | Functional | Potentiation of K+ stimulated release of [3H]-5-HT from brain slices at a concentration of 10 nM. (activity expressed as ratio of S2 (second stimulation)/S1(first stimulation)) | Rattus norvegicus | 1 | ALA1131235 | tissue-based format | Scientific Literature | |
17. | ALA651424 | Functional | Antagonism of the induced potentiation of K+ stimulated [3H]5-HT release from brain slices with 5-HT (1000 nM) at a concentration of 1000 nM. | Rattus norvegicus | 1 | ALA1131235 | tissue-based format | Scientific Literature | |
18. | ALA651425 | Functional | Antagonism of the induced potentiation of K+ stimulated [3H]5-HT release from brain slices with 5-HT (100 nM) at a concentration of 1000 nM. | Rattus norvegicus | 1 | ALA1131235 | tissue-based format | Scientific Literature | |
19. | ALA651426 | Functional | Percent control of the stimulation ratio S2 (second stimulation)/S1(first stimulation) at a concentration of 1000 nM. (p<0.05) | Rattus norvegicus | 1 | ALA1131235 | assay format | Scientific Literature | |
20. | ALA651427 | Functional | Percent control of the stimulation ratio S2 (second stimulation)/S1(first stimulation) at a concentration of 100 nM. (P<0.05) | Rattus norvegicus | 1 | ALA1131235 | assay format | Scientific Literature |