| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA628160 | A | Evaluated for first order rate constant (Kin) for transcorneal penetration in anesthetized rabbits | Oryctolagus cuniculus | 8 | ALA1123893 | organism-based format | Scientific Literature | |
| 2. | ALA858429 | P | Partition coefficient (logP) | 2 | ALA1121604 | small-molecule physicochemical format | Scientific Literature | ||
| 3. | ALA628376 | A | In vitro susceptibility to nucleophilic attack by reduced glutathione at 37 degree C and at pH 7.4 | 9 | ALA1124628 | assay format | Scientific Literature | ||
| 4. | ALA634767 | A | Compound was evaluated for its solubility in water | 11 | ALA1123893 | assay format | Scientific Literature | ||
| 5. | ALA637297 | P | Evaluated for lipid solubility measured as partition coefficient at a pH 7.4 (CHCl3/buffer) | 11 | ALA1123893 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA639394 | A | Tested for solubility in pH 7.4 buffer, at 25 Degree C | 5 | ALA1133531 | assay format | Scientific Literature | ||
| 7. | ALA631756 | P | Solubility (in uM) in pH 7.40 at 25 degree C | 6 | ALA1133556 | small-molecule physicochemical format | Scientific Literature | ||
| 8. | ALA633371 | P | The solubility at pH 7.40 and 25 degree Centigrade was evaluated. | 10 | ALA1132382 | small-molecule physicochemical format | Scientific Literature | ||
| 9. | ALA633550 | P | Lipophilicity of the compound | 14 | ALA1135800 | small-molecule physicochemical format | Scientific Literature | ||
| 10. | ALA633167 | P | Evaluated for sulfonamide pKa, free acid water solubility | 11 | ALA1123893 | small-molecule physicochemical format | Scientific Literature | ||
| 11. | ALA634030 | A | The compound was evaluated for in Vitro corneal permeability at cornea intact | 10 | ALA1132382 | tissue-based format | Scientific Literature | ||
| 12. | ALA634031 | A | The compound was evaluated for in Vitro corneal permeability when no epithelium | 10 | ALA1132382 | tissue-based format | Scientific Literature | ||
| 13. | ALA876218 | P | pKa of the compound was determined | 5 | ALA1121604 | small-molecule physicochemical format | Scientific Literature | ||
| 14. | ALA635344 | P | Partition coefficient (logD) (chloroform/buffer) | 10 | ALA1132382 | small-molecule physicochemical format | Scientific Literature | ||
| 15. | ALA635940 | P | Partition coefficient (logD) (chloroform/buffer) | 4 | ALA1133531 | assay format | Scientific Literature | ||
| 16. | ALA637490 | P | Calculated partition coefficient (clogP) (MlogP) | 35 | ALA1135542 | small-molecule physicochemical format | Scientific Literature | ||
| 17. | ALA638172 | P | Partition coefficient (logD) (chloroform/buffer) | 11 | ALA1133556 | small-molecule physicochemical format | Scientific Literature | ||
| 18. | ALA653166 | B | Inhibition of human recombinant carbonic anhydrase I | 31 | ALA1144996 | single protein format | Scientific Literature | ||
| 19. | ALA653167 | B | Inhibition of human recombinant carbonic anhydrase I (CA1) | 151 | ALA1133531 | single protein format | Scientific Literature | ||
| 20. | ALA653175 | B | Compound was evaluated for inhibition against human carbonic anhydrase II | 6 | ALA1146695 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!