# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA689401 | Functional | Effect on total serum cholesterol in male hamsters at a dose of 10 mg/kg orally administered for 14 days | Cricetulus griseus | 3 | ALA1127068 | organism-based format | Scientific Literature | |
2. | ALA692827 | Functional | Effect on total serum cholesterol in male hamsters at a dose of 100 mg/kg orally administered for 14 days | Cricetulus griseus | 4 | ALA1127068 | organism-based format | Scientific Literature | |
3. | ALA692831 | Functional | Effect on total serum cholesterol in male hamsters at a dose of 25 mg/kg orally administered for 14 days | Cricetulus griseus | 5 | ALA1127068 | organism-based format | Scientific Literature | |
4. | ALA692834 | Functional | Effect on total serum cholesterol in male hamsters at a dose of 50 mg/kg orally administered for 14 days | Cricetulus griseus | 5 | ALA1127068 | organism-based format | Scientific Literature | |
5. | ALA692835 | Functional | Effect on total serum cholesterol in male hamsters at a dose of 60 mg/kg orally administered for 3 days | Cricetulus griseus | 2 | ALA1127068 | organism-based format | Scientific Literature | |
6. | ALA879717 | Functional | Percentage increase of the total serum cholesterol in male hamsters at a dose of 10 mg/dL orally administered for 14 days | Cricetulus griseus | 1 | ALA1127068 | organism-based format | Scientific Literature | |
7. | ALA696212 | Functional | Percentage increase of the total serum cholesterol in male hamsters at a dose of 25 mg/dL orally administered for 14 days | Cricetulus griseus | 2 | ALA1127068 | organism-based format | Scientific Literature | |
8. | ALA694377 | Functional | Percentage lowering of the total serum cholesterol in male hamsters at a dose of 100 mg/dL orally administered for 14 days | Cricetulus griseus | 3 | ALA1127068 | organism-based format | Scientific Literature | |
9. | ALA690604 | Functional | Percentage lowering of the total serum cholesterol in male hamsters at a dose of 50 mg/dL orally administered for 14 days | Cricetulus griseus | 4 | ALA1127068 | organism-based format | Scientific Literature | |
10. | ALA690759 | Functional | Percentage lowering of the total serum cholesterol in male hamsters at a dose of 60 mg/dL orally administered for 3 days | Cricetulus griseus | 1 | ALA1127068 | organism-based format | Scientific Literature | |
11. | ALA705388 | Binding | Apparent Ki for rat Lanosterol 14-alpha demethylase | Rattus norvegicus | 2 | ALA1127068 | single protein format | Scientific Literature | |
12. | ALA1015210 | Binding | Inhibition of heme oxygenase-1 in Sprague-Dawley rat spleen microsomal fraction assessed as carbon monoxide formation by gas chromatography | Rattus norvegicus | 35 | ALA1152815 | microsome format | Scientific Literature | |
13. | ALA1015211 | Binding | Inhibition of heme oxygenase-2 in Sprague-Dawley rat brain microsomal fraction assessed as carbon monoxide formation by gas chromatography | Rattus norvegicus | 34 | ALA1152815 | microsome format | Scientific Literature | |
14. | ALA1015212 | Binding | Selectivity index, ratio of IC50 for Sprague-Dawley rat brain heme oxygenase-2 to IC50 for Sprague-Dawley rat spleen heme oxygenase-1 | Rattus norvegicus | 34 | ALA1152815 | tissue-based format | Scientific Literature | |
15. | ALA827964 | Binding | In vitro inhibitory concentration against heme oxygenase 2 from rat brain | Rattus norvegicus | 12 | ALA1142016 | assay format | Scientific Literature | |
16. | ALA829463 | Binding | In vitro inhibitory concentration against heme oxygenase 1 from rat spleen | Rattus norvegicus | 12 | ALA1142016 | single protein format | Scientific Literature | |
17. | ALA830832 | Binding | Relative binding affinity to rat heme oxygenases 1 and 2 | Rattus norvegicus | 9 | ALA1142016 | assay format | Scientific Literature | |
18. | ALA4403458 | Binding | Inhibition of Sprague-Dawley rat spleen microsome HO-1 preincubated for 10 mins followed by beta-NADPH addition and measured after 15 mins by gas chromatography | Rattus norvegicus | 35 | ALA4402532 | microsome format | Scientific Literature | |
19. | ALA4403459 | Binding | Inhibition of Sprague-Dawley rat brain microsome HO-2 preincubated for 10 mins followed by beta-NADPH addition and measured after 15 mins by gas chromatography | Rattus norvegicus | 35 | ALA4402532 | microsome format | Scientific Literature |