# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1762926 | B | Displacement of [3H]dapagliflozin from human SGLT2 expressed in CHO cells after 60 mins by scintillation counting | Homo sapiens | 2 | ALA1759842 | cell-based format | Scientific Literature | |
2. | ALA1762927 | A | Metabolic stability in rat liver microsomes assessed as compound remaining after 30 mins | Rattus norvegicus | 2 | ALA1759842 | microsome format | Scientific Literature | |
3. | ALA1762928 | A | Metabolic stability in human liver microsomes assessed as compound remaining after 30 mins | Homo sapiens | 2 | ALA1759842 | microsome format | Scientific Literature | |
4. | ALA1763178 | B | Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillation counting | Homo sapiens | 24 | ALA1759842 | cell-based format | Scientific Literature | |
5. | ALA1763179 | B | Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillation counting | Homo sapiens | 24 | ALA1759842 | cell-based format | Scientific Literature | |
6. | ALA1763184 | B | Selectivity ratio of IC50 for human SGLT2 to human SGLT1 expressed in CHO cells | Homo sapiens | 3 | ALA1759842 | cell-based format | Scientific Literature | |
7. | ALA1763187 | B | Inhibition of SGLT6 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillation counting | 3 | ALA1759842 | cell-based format | Scientific Literature | ||
8. | ALA1763188 | B | Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillation counting in presence of 100% plasma | Homo sapiens | 3 | ALA1759842 | cell-based format | Scientific Literature | |
9. | ALA1763189 | B | Selectivity ratio of IC50 for human SGLT2 to human SGLT6 expressed in CHO cells | Homo sapiens | 2 | ALA1759842 | cell-based format | Scientific Literature |