| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1762926 | B | Displacement of [3H]dapagliflozin from human SGLT2 expressed in CHO cells after 60 mins by scintillation counting | Homo sapiens | 2 | ALA1759842 | cell-based format | Scientific Literature | |
| 2. | ALA1762927 | A | Metabolic stability in rat liver microsomes assessed as compound remaining after 30 mins | Rattus norvegicus | 2 | ALA1759842 | microsome format | Scientific Literature | |
| 3. | ALA1762928 | A | Metabolic stability in human liver microsomes assessed as compound remaining after 30 mins | Homo sapiens | 2 | ALA1759842 | microsome format | Scientific Literature | |
| 4. | ALA1763178 | B | Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillation counting | Homo sapiens | 24 | ALA1759842 | cell-based format | Scientific Literature | |
| 5. | ALA1763179 | B | Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillation counting | Homo sapiens | 24 | ALA1759842 | cell-based format | Scientific Literature | |
| 6. | ALA1763184 | B | Selectivity ratio of IC50 for human SGLT2 to human SGLT1 expressed in CHO cells | Homo sapiens | 3 | ALA1759842 | cell-based format | Scientific Literature | |
| 7. | ALA1763187 | B | Inhibition of SGLT6 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillation counting | 3 | ALA1759842 | cell-based format | Scientific Literature | ||
| 8. | ALA1763188 | B | Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillation counting in presence of 100% plasma | Homo sapiens | 3 | ALA1759842 | cell-based format | Scientific Literature | |
| 9. | ALA1763189 | B | Selectivity ratio of IC50 for human SGLT2 to human SGLT6 expressed in CHO cells | Homo sapiens | 2 | ALA1759842 | cell-based format | Scientific Literature | |
| 10. | ALA1781790 | B | Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-Glucose uptake using [14C]-methyl glucopyranoside after 60 mins by microbeta plate counting | Homo sapiens | 33 | ALA1777714 | cell-based format | Scientific Literature | |
| 11. | ALA1781791 | A | Metabolic stability in rat liver microsomes assessed as compound remaining at 1 uM after 30 mins by liquid chromatography/mass spectrometry analysis | Rattus norvegicus | 26 | ALA1777714 | microsome format | Scientific Literature | |
| 12. | ALA1781792 | A | Metabolic stability in human liver microsomes assessed as compound remaining at 1 uM after 30 mins by liquid chromatography/mass spectrometry analysis | Homo sapiens | 26 | ALA1777714 | microsome format | Scientific Literature | |
| 13. | ALA1781793 | P | Solubility of the compound in phosphate buffered saline | 10 | ALA1777714 | small-molecule physicochemical format | Scientific Literature | ||
| 14. | ALA1781794 | A | Metabolic stability in mouse liver microsomes assessed as compound remaining at 1 uM after 30 mins by liquid chromatography/mass spectrometry analysis | Mus musculus | 8 | ALA1777714 | microsome format | Scientific Literature | |
| 15. | ALA1781796 | B | Inhibition of human SGLT1 | Homo sapiens | 3 | ALA1777714 | single protein format | Scientific Literature |
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