# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1764816 | Binding | Inhibition of human EPHB4 | Homo sapiens | 32 | ALA1759854 | single protein format | Scientific Literature | |
2. | ALA1764817 | Binding | Inhibition FGFR1 | 16 | ALA1759854 | single protein format | Scientific Literature | ||
3. | ALA1764818 | Binding | Inhibition of VEGFR2 | 15 | ALA1759854 | single protein format | Scientific Literature | ||
4. | ALA1764819 | Binding | Inhibition of human EphB4 autophosphorylation expressed in CHOK1 cells | Homo sapiens | 32 | ALA1759854 | cell-based format | Scientific Literature | |
5. | ALA1764820 | Physicochemical | Lipophilicity, log D of the compound | 18 | ALA1759854 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA1764821 | ADME | Fraction unbound in human plasma | Homo sapiens | 3 | ALA1759854 | cell-free format | Scientific Literature | |
7. | ALA1764822 | ADME | Clearance in Han Wistar rat assessed as liver blood flow at 1 or 2.5 mg/kg, iv and 5 or 10 mg/kg, po | Rattus norvegicus | 3 | ALA1759854 | organism-based format | Scientific Literature | |
8. | ALA1764880 | ADME | Volume of distribution at steady state in Han Wistar rat at 1 or 2.5 mg/kg, iv and 5 or 10 mg/kg, po | Rattus norvegicus | 3 | ALA1759854 | organism-based format | Scientific Literature | |
9. | ALA1764882 | ADME | Oral bioavailability in Han Wistar rat at 5 or 10 mg/kg, po | Rattus norvegicus | 3 | ALA1759854 | organism-based format | Scientific Literature | |
10. | ALA1764883 | ADME | Clearance in Beagle dog assessed as liver blood flow at 2 umol/kg, iv and 5 umol/kg, po | Canis lupus familiaris | 2 | ALA1759854 | organism-based format | Scientific Literature | |
11. | ALA1764884 | ADME | Volume of distribution at steady state in Beagle dog at 2 umol/kg, iv and 5 umol/kg, po | Canis lupus familiaris | 2 | ALA1759854 | organism-based format | Scientific Literature | |
12. | ALA1764885 | ADME | Oral bioavailability in Beagle dog at 5 umol/kg, po | Canis lupus familiaris | 2 | ALA1759854 | organism-based format | Scientific Literature | |
13. | ALA1764886 | ADME | AUC in nude mouse at 10 umol/kg, po | Mus musculus | 1 | ALA1759854 | organism-based format | Scientific Literature | |
14. | ALA1764887 | ADME | Cmax in nude mouse at 10 umol/kg, po | Mus musculus | 1 | ALA1759854 | organism-based format | Scientific Literature | |
15. | ALA1764888 | Binding | Inhibition of SRC at 10 uM | 1 | ALA1759854 | single protein format | Scientific Literature | ||
16. | ALA1764889 | Binding | Inhibition of LCK at 10 uM | 1 | ALA1759854 | single protein format | Scientific Literature | ||
17. | ALA1763675 | Binding | Inhibition of CSK at 10 uM | 1 | ALA1759854 | single protein format | Scientific Literature | ||
18. | ALA1763676 | Binding | Inhibition of SRC | 1 | ALA1759854 | single protein format | Scientific Literature | ||
19. | ALA1763677 | Binding | Inhibition of LCK | 1 | ALA1759854 | single protein format | Scientific Literature | ||
20. | ALA1763678 | Binding | Inhibition of CSK | 1 | ALA1759854 | single protein format | Scientific Literature |