# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1769552 | B | Displacement of [3H]DPDPE from human delta opioid receptor expressed in mouse HN9.10 cells | Homo sapiens | 6 | ALA1765015 | cell-based format | Scientific Literature | |
2. | ALA1769553 | B | Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cells | Rattus norvegicus | 6 | ALA1765015 | cell-based format | Scientific Literature | |
3. | ALA1769554 | B | Selectivity ratio of Ki for rat mu opioid receptor to Ki for human delta opioid receptor | 6 | ALA1765015 | assay format | Scientific Literature | ||
4. | ALA1769555 | B | Displacement of [3H]substance P from human NK1 receptor expressed in CHO cells | Homo sapiens | 6 | ALA1765015 | cell-based format | Scientific Literature | |
5. | ALA1769556 | B | Displacement of [3H]substance P from rat NK1 receptor expressed in CHO cells | Rattus norvegicus | 6 | ALA1765015 | cell-based format | Scientific Literature | |
6. | ALA1769557 | B | Selectivity ratio of Ki for rat NK1 receptor to Ki for human NK1 receptor | 6 | ALA1765015 | assay format | Scientific Literature | ||
7. | ALA1769558 | F | Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contraction | Mus musculus | 6 | ALA1765015 | tissue-based format | Scientific Literature | |
8. | ALA1769559 | F | Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contraction | Cavia porcellus | 6 | ALA1765015 | tissue-based format | Scientific Literature | |
9. | ALA1769560 | F | Antagonist activity at NK1 receptor in guinea pig ileum assessed as inhibition of substance P-induced muscle contraction | Cavia porcellus | 6 | ALA1765015 | tissue-based format | Scientific Literature | |
10. | ALA1769561 | F | Agonist activity at human opioid delta receptor expressed in mouse HN9.10 cells assessed as [35S]GTPgammaS binding | Homo sapiens | 6 | ALA1765015 | cell-based format | Scientific Literature | |
11. | ALA1769562 | F | Agonist activity at human opioid delta receptor expressed in mouse HN9.10 cells assessed as [35S]GTPgammaS binding relative to control | Homo sapiens | 6 | ALA1765015 | cell-based format | Scientific Literature | |
12. | ALA1769563 | F | Agonist activity at rat mu opioid receptor expressed in mouse HN9.10 cells assessed as [35S]GTPgammaS binding | Rattus norvegicus | 6 | ALA1765015 | cell-based format | Scientific Literature | |
13. | ALA1769597 | F | Agonist activity at rat mu opioid receptor expressed in mouse HN9.10 cells assessed as [35S]GTPgammaS binding relative to control | Rattus norvegicus | 6 | ALA1765015 | cell-based format | Scientific Literature | |
14. | ALA1769598 | A | Metabolic stability in rat plasma after up to 6 hrs | Rattus norvegicus | 1 | ALA1765015 | cell-free format | Scientific Literature | |
15. | ALA1769599 | F | Antinociceptive activity in Sprague-Dawley rat assessed as reduction in infrared heat-induced paw withdrawal latency at 10 ug administered intrathecally after 60 mins (Rvb = 7 +/- 5.7%) | Rattus norvegicus | 1 | ALA1765015 | organism-based format | Scientific Literature | |
16. | ALA1769600 | F | Antinociceptive activity in Sprague-Dawley rat assessed as time required to maximum activity on reduction in infrared heat-induced paw withdrawal latency at 10 ug administered intrathecally | Rattus norvegicus | 3 | ALA1765015 | organism-based format | Scientific Literature |