# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1768668 | B | Inhibition of purified recombinant c-Met after 60 mins by ELISA | 33 | ALA1765011 | single protein format | Scientific Literature | ||
2. | ALA1768670 | F | Antiproliferative activity against mouse BAF3 cells expressing TPR-Met after 72 hrs in presence of IL-3 | Mus musculus | 7 | ALA1765011 | cell-based format | Scientific Literature | |
3. | ALA1768671 | B | Inhibition of TPR-MET autophosphorylation in mouse NIH3T3 cells after 4 hrs by Western blotting | Mus musculus | 6 | ALA1765011 | cell-based format | Scientific Literature | |
4. | ALA1768672 | B | Inhibition of TPR-MET autophosphorylation in mouse BaF3 cells after 4 hrs by Western blotting | Mus musculus | 6 | ALA1765011 | cell-based format | Scientific Literature | |
5. | ALA1768673 | F | Antiproliferative activity against mouse BAF3 cells expressing TPR-Met after 72 hrs in absence of IL-3 | Mus musculus | 7 | ALA1765011 | cell-based format | Scientific Literature | |
6. | ALA1768674 | F | Antiproliferative activity against mouse NIH/3T3 cells expressing TPR-Met after 72 hrs | Mus musculus | 7 | ALA1765011 | cell-based format | Scientific Literature | |
7. | ALA1768675 | F | Antiproliferative activity against mouse NIH/3T3 cells after 72 hrs | Mus musculus | 7 | ALA1765011 | cell-based format | Scientific Literature | |
8. | ALA1768676 | A | Clearance in mouse at 10 mg/kg, iv | Mus musculus | 2 | ALA1765011 | organism-based format | Scientific Literature | |
9. | ALA1768678 | A | Volume of distribution at steady state in mouse at 10 mg/kg, iv | Mus musculus | 2 | ALA1765011 | organism-based format | Scientific Literature | |
10. | ALA1768680 | A | Half life in mouse at 10 mg/kg, iv | Mus musculus | 2 | ALA1765011 | organism-based format | Scientific Literature | |
11. | ALA1768682 | A | Cmax in mouse at 20 mg/kg, po | Mus musculus | 3 | ALA1765011 | organism-based format | Scientific Literature | |
12. | ALA1768683 | A | Tmax in mouse at 20 mg/kg, po | Mus musculus | 3 | ALA1765011 | organism-based format | Scientific Literature | |
13. | ALA1768684 | A | AUC (0 to infinity) in mouse at 20 mg/kg, po | Mus musculus | 3 | ALA1765011 | organism-based format | Scientific Literature | |
14. | ALA1768685 | A | Oral bioavailability in mouse at 20 mg/kg | Mus musculus | 3 | ALA1765011 | organism-based format | Scientific Literature | |
15. | ALA1768686 | B | Inhibition of RON | 1 | ALA1765011 | single protein format | Scientific Literature | ||
16. | ALA1768687 | B | Inhibition of Flt-1 | 1 | ALA1765011 | single protein format | Scientific Literature | ||
17. | ALA1768688 | B | Inhibition of KDR | 1 | ALA1765011 | single protein format | Scientific Literature | ||
18. | ALA1768689 | B | Inhibition of c-Kit | 1 | ALA1765011 | single protein format | Scientific Literature | ||
19. | ALA1768690 | B | Inhibition of PDGFRalpha | 1 | ALA1765011 | single protein format | Scientific Literature | ||
20. | ALA1768691 | B | Inhibition of RET | 1 | ALA1765011 | single protein format | Scientific Literature |