# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1769161 | F | Induction of apoptosis in human MCF7 cells assessed as aberrant gross morphological changes at 10 uM after 48 hrs using propidium iodide staining by confocal microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA1769162 | F | Induction of apoptosis in human MCF7 cells assessed as decrease in cell number at 10 uM after 48 hrs using propidium iodide staining by confocal microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
3. | ALA1768836 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as aberrant gross morphological changes at 10 uM after 48 hrs using propidium iodide staining by confocal microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA1768837 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as decrease in cell number at 10 uM after 48 hrs using propidium iodide staining by confocal microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA1768842 | F | Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 48 hrs by WST-1 assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA1768844 | F | Antiproliferative activity against estrogen receptor-deficient human MDA-MB-231 cells after 48 hrs by WST-1 assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
7. | ALA1768845 | B | Inhibition of at human CDK9/cyclin T1 at 0.1 uM after 40 mins relative to control | Homo sapiens | 4 | protein complex format | Scientific Literature | ||
8. | ALA1768846 | B | Inhibition of human CDK7/cyclinH/MAT1 at 0.1 uM after 40 mins relative to control | Homo sapiens | 4 | protein complex format | Scientific Literature | ||
9. | ALA1768847 | B | Inhibition of human CDK5/p35 at 0.1 uM after 40 mins relative to control | Homo sapiens | 4 | protein complex format | Scientific Literature | ||
10. | ALA1768848 | B | Inhibition of human CDK3/cyclin E at 0.1 uM after 40 mins relative to control | Homo sapiens | 4 | protein complex format | Scientific Literature | ||
11. | ALA1768849 | B | Inhibition of human CDK5/p25 at 0.1 uM after 40 mins relative to control | Homo sapiens | 4 | protein complex format | Scientific Literature | ||
12. | ALA1768850 | B | Inhibition of human CDK2/cyclin E at 0.1 uM after 40 mins relative to control | Homo sapiens | 4 | protein complex format | Scientific Literature | ||
13. | ALA1768851 | B | Inhibition of human CDK2/cyclin A at 0.1 uM after 40 mins relative to control | Homo sapiens | 4 | protein complex format | Scientific Literature | ||
14. | ALA1768852 | B | Inhibition of human CDK1/cyclin B at 0.1 uM after 40 mins relative to control | Homo sapiens | 4 | protein complex format | Scientific Literature | ||
15. | ALA1768853 | F | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at G2/M phase at 5 to 10 uM after 24 hrs using propidium iodide staining by flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA1768854 | F | Cell cycle arrest in human MCF7 cells assessed as accumulation at G2/M phase at 5 to 10 uM after 24 hrs using propidium iodide staining by flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA1768855 | F | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at sup G1 phase at 5 to 10 uM after 24 hrs using propidium iodide staining by flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA1768856 | F | Cell cycle arrest in human MCF7 cells assessed as accumulation at sub G1 phase at 5 to 10 uM after 24 hrs using propidium iodide staining by flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA1768857 | F | Cell cycle arrest in human MCF7 cells assessed as accumulation at G2/M phase at 5 to 10 uM after 16 to 40 hrs using propidium iodide staining by flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA1767499 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as decrease in Bcl2 protein level at 10 uM after 48 hrs by Western blotting | Homo sapiens | 2 | cell-based format | Scientific Literature |