| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1771831 | B | Inhibition of human recombinant BACE-1 expressed in HEK293 cells assessed as inhibition of amyloid precursor protein cleavage into amyloid beta after 60 mins using Rh-EVNLDAEFK-Quencher as a substrate by FRET assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 2. | ALA3071787 | B | Inhibition of BuChE (unknown origin) | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 3. | ALA3071788 | B | Inhibition of AChE (unknown origin) | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 4. | ALA3871056 | T | Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 25 ug/ml measured after 24 hrs in presence of LPS by MTT assay (Rvb = 96.3 +/- 1%) | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 5. | ALA3871057 | T | Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 12.5 ug/ml measured after 24 hrs in presence of LPS by MTT assay (Rvb = 96.3 +/- 1%) | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 6. | ALA3871058 | F | Antiplatelet aggregatory activity against New Zealand white rabbit platelets at 100 uM preincubated for 2 to 3 mins followed by ADP-addition measured after 4 mins by turbidometric method relative to vehicle control | Oryctolagus cuniculus | 9 | cell-based format | Scientific Literature | ||
| 7. | ALA3871060 | F | Antiplatelet aggregatory activity against New Zealand white rabbit platelets at 100 uM preincubated for 2 to 3 mins followed by arachidonic acid -addition measured after 4 mins by turbidometric method relative to vehicle control | Oryctolagus cuniculus | 9 | cell-based format | Scientific Literature | ||
| 8. | ALA3871062 | F | Antiplatelet aggregatory activity against New Zealand white rabbit platelets at 100 uM preincubated for 2 to 3 mins followed by PAF-addition measured after 4 mins by turbidometric method relative to vehicle control | Oryctolagus cuniculus | 9 | cell-based format | Scientific Literature | ||
| 9. | ALA3871067 | T | Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 3.125 ug/ml measured after 24 hrs in presence of LPS by MTT assay (Rvb = 96.3 +/- 1%) | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 10. | ALA3871068 | T | Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 6.25 ug/ml measured after 24 hrs in presence of LPS by MTT assay (Rvb = 96.3 +/- 1%) | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 11. | ALA3871069 | T | Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 50 ug/ml measured after 24 hrs in presence of LPS by MTT assay (Rvb = 96.3 +/- 1%) | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 12. | ALA3871072 | F | Inhibition of LPS-induced NO production in mouse RAW264.7 cells at 3.125 ug/ml measured after 24 hrs by Griess assay relative to LPS-treated control | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 13. | ALA3871073 | F | Inhibition of LPS-induced NO production in mouse RAW264.7 cells at 6.25 ug/ml measured after 24 hrs by Griess assay relative to LPS-treated control | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 14. | ALA3871076 | F | Inhibition of LPS-induced NO production in mouse RAW264.7 cells measured after 24 hrs by Griess assay | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 15. | ALA5143171 | F | Antibacterial activity against Escherichia coli ATCC 25922 assessed as inhibition of bacterial growth incubated for 24 hrs by optical density based analysis | Escherichia coli | 6 | organism-based format | Scientific Literature | ||
| 16. | ALA5143172 | F | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as inhibition of bacterial growth incubated for 24 hrs by optical density based analysis | Staphylococcus aureus | 6 | organism-based format | Scientific Literature | ||
| 17. | ALA5143173 | F | Antibacterial activity against Staphylococcus epidermidis ATCC 51625 assessed as inhibition of bacterial growth incubated for 24 hrs by optical density based analysis | Staphylococcus epidermidis | 6 | organism-based format | Scientific Literature | ||
| 18. | ALA5143174 | F | Antibacterial activity against Bacillus subtilis ATCC 11774 assessed as inhibition of bacterial growth incubated for 24 hrs by optical density based analysis | Bacillus subtilis | 6 | organism-based format | Scientific Literature | ||
| 19. | ALA5143175 | F | Antibacterial activity against Escherichia coli assessed as inhibition of bacterial growth incubated for 18 hrs by p-iodonitrotetrazolium chloride dye based colorimetric assay | Escherichia coli | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA5143176 | F | Antibacterial activity against Enterobacter aerogenes assessed as inhibition of bacterial growth incubated for 18 hrs by p-iodonitrotetrazolium chloride dye based colorimetric assay | Klebsiella aerogenes | 1 | organism-based format | Scientific Literature |
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