# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2038927 | A | Oral bioavailability in Sprague-Dawley rat at 2 mg/kg | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
2. | ALA2039029 | F | Antagonist activity against human EP2 receptor expressed in CHO-K1 cells assessed as inhibition of cAMP production after 4 hrs by FRET signal in LANCE assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA2039030 | F | Antagonist activity at EP1 receptor in human U2OS cells expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs by FLIPR assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA2039031 | F | Antagonist activity at dog EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs by FLIPR assay | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
5. | ALA2039032 | F | Inhibition of GR63799-induced decrease in bladder capacity in conscious spontaneously hypertensive overactive bladder rat model at 3 mg/kg, id | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
6. | ALA2039034 | A | Drug metabolism in rat liver S9 fraction assessed as NADPH-dependent glutathione conjugate level at 10 uM after 30 mins by LC-MS/MS analysis | Rattus norvegicus | 4 | subcellular format | Scientific Literature | ||
7. | ALA2039035 | A | Drug metabolism in human liver S9 fraction assessed as NADPH-dependent glutathione conjugate level at 10 uM after 30 mins by LC-MS/MS analysis | Homo sapiens | 4 | subcellular format | Scientific Literature | ||
8. | ALA2039036 | F | Inhibition of GR63799-induced decrease in bladder capacity in conscious spontaneously hypertensive overactive bladder rat model at 0.3 mg/kg, id | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
9. | ALA2039037 | F | Inhibition of PGE2-induced decrease in bladder capacity in conscious spontaneously hypertensive overactive bladder rat model at 30 mg/kg, id | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
10. | ALA2039038 | F | Inhibition of acetic acid-induced decrease in bladder capacity in conscious spontaneously hypertensive overactive bladder rat model at 30 mg/kg, id | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
11. | ALA2039039 | B | Binding affinity to human EP3 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
12. | ALA2039040 | A | Half life in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
13. | ALA2039041 | A | Clearance in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
14. | ALA2039043 | F | Inhibition of saline-induced bladder rhythmic contraction in anesthetized iv dosed Sprague-Dawley rat model | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
15. | ALA2039044 | F | Inhibition of GR63799-induced decrease in bladder capacity in conscious spontaneously hypertensive overactive bladder rat model at 30 mg/kg, id | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
16. | ALA2039045 | F | Antagonist activity at FP receptor in human U2OS cells expressing Gqi5 assessed as inhibition of PGE2-induced response after 48 hrs by FLIPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA2039046 | B | Binding affinity at human DP receptor | Homo sapiens | 1 | single protein format | Scientific Literature | ||
18. | ALA2039047 | B | Binding affinity at human EP4 receptor | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA2039048 | B | Inhibition of COX2 in rat whole blood assessed as decreased PGE2 production | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
20. | ALA2039049 | P | Aqueous solubility of the compound | 1 | small-molecule physicochemical format | Scientific Literature |