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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA1771833 Functional Antagonist activity at human EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium concentration after 1 hr by FLIPR assay Homo sapiens 26 ALA1770146 cell-based format Scientific Literature 2. ALA1771834 ADME Clearance in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po Rattus norvegicus 3 ALA1770146 organism-based format Scientific Literature 3. ALA1771835 ADME Half life in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po Rattus norvegicus 3 ALA1770146 organism-based format Scientific Literature 4. ALA1771836 ADME Dose normalized AUC in Sprague-Dawley rat at 2 mg/kg, po Rattus norvegicus 3 ALA1770146 organism-based format Scientific Literature 5. ALA1771837 ADME Oral bioavailability in Sprague-Dawley rat at 2 mg/kg Rattus norvegicus 3 ALA1770146 organism-based format Scientific Literature 6. ALA1771838 Functional Antagonist activity at dog EP3 receptor Canis lupus familiaris 1 ALA1770146 assay format Scientific Literature 7. ALA1771839 Functional Antagonist activity at rat EP3 receptor Rattus norvegicus 1 ALA1770146 assay format Scientific Literature 8. ALA2038927 ADME Oral bioavailability in Sprague-Dawley rat at 2 mg/kg Rattus norvegicus 5 ALA2034937 organism-based format Scientific Literature 9. ALA2039029 Functional Antagonist activity against human EP2 receptor expressed in CHO-K1 cells assessed as inhibition of cAMP production after 4 hrs by FRET signal in LANCE assay Homo sapiens 1 ALA2034937 cell-based format Scientific Literature 10. ALA2039030 Functional Antagonist activity at EP1 receptor in human U2OS cells expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs by FLIPR assay Homo sapiens 2 ALA2034937 cell-based format Scientific Literature 11. ALA2039031 Functional Antagonist activity at dog EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs by FLIPR assay Canis lupus familiaris 1 ALA2034937 cell-based format Scientific Literature 12. ALA2039032 Functional Inhibition of GR63799-induced decrease in bladder capacity in conscious spontaneously hypertensive overactive bladder rat model at 3 mg/kg, id Rattus norvegicus 1 ALA2034937 organism-based format Scientific Literature 13. ALA2039034 ADME Drug metabolism in rat liver S9 fraction assessed as NADPH-dependent glutathione conjugate level at 10 uM after 30 mins by LC-MS/MS analysis Rattus norvegicus 4 ALA2034937 subcellular format Scientific Literature 14. ALA2039035 ADME Drug metabolism in human liver S9 fraction assessed as NADPH-dependent glutathione conjugate level at 10 uM after 30 mins by LC-MS/MS analysis Homo sapiens 4 ALA2034937 subcellular format Scientific Literature 15. ALA2039036 Functional Inhibition of GR63799-induced decrease in bladder capacity in conscious spontaneously hypertensive overactive bladder rat model at 0.3 mg/kg, id Rattus norvegicus 1 ALA2034937 organism-based format Scientific Literature 16. ALA2039037 Functional Inhibition of PGE2-induced decrease in bladder capacity in conscious spontaneously hypertensive overactive bladder rat model at 30 mg/kg, id Rattus norvegicus 1 ALA2034937 organism-based format Scientific Literature 17. ALA2039038 Functional Inhibition of acetic acid-induced decrease in bladder capacity in conscious spontaneously hypertensive overactive bladder rat model at 30 mg/kg, id Rattus norvegicus 1 ALA2034937 organism-based format Scientific Literature 18. ALA2039039 Binding Binding affinity to human EP3 Homo sapiens 1 ALA2034937 single protein format Scientific Literature 19. ALA2039040 ADME Half life in Sprague-Dawley rat at 1 mg/kg, iv Rattus norvegicus 5 ALA2034937 organism-based format Scientific Literature 20. ALA2039041 ADME Clearance in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po Rattus norvegicus 5 ALA2034937 organism-based format Scientific Literature