# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA653553 | F | Ability to inhibit 3H substance P binding to bovine retina was evaluated | Bos taurus | 3 | ALA1129770 | organism-based format | Scientific Literature | |
2. | ALA671392 | B | Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluated | Sus scrofa | 15 | ALA1129770 | tissue-based format | Scientific Literature | |
3. | ALA671393 | B | Binding affinity to Endothelin B receptor | Cavia porcellus | 26 | ALA1131547 | single protein format | Scientific Literature | |
4. | ALA682952 | B | Ability to inhibit [125I]ET1 binding to the Endothelin A receptor from porcine lung membranes was evaluated | 14 | ALA1129770 | tissue-based format | Scientific Literature | ||
5. | ALA682954 | B | Binding affinity to Endothelin A receptor | Cavia porcellus | 26 | ALA1131547 | single protein format | Scientific Literature | |
6. | ALA852000 | B | Ratio of endothelin A binding affinity to endothelin B binding affinity | Cavia porcellus | 26 | ALA1131547 | assay format | Scientific Literature | |
7. | ALA4199826 | B | Binding affinity to hemoglobin (unknown origin) assessed as increase in release of carbon monooxide from carboxyhemoglobin by measuring half life of carboxyhemoglobin at 20:1 compound/Hb tetramer ratio incubated for 1 hr measured every 15 mins for 90 mins (Rvb = 80 +/- 0.3 min) | Homo sapiens | 11 | ALA4196122 | protein complex format | Scientific Literature | |
8. | ALA4199827 | B | Binding affinity to hemoglobin (unknown origin) assessed as increase in release of carbon monooxide from carboxyhemoglobin by measuring half life of carboxyhemoglobin at 5:1 compound/Hb tetramer ratio incubated for 1 hr measured every 15 mins for 90 mins (Rvb = 80 +/- 0.3 min) | Homo sapiens | 11 | ALA4196122 | protein complex format | Scientific Literature | |
9. | ALA4199828 | A | Hemolytic activity against human RBC assessed as fraction of extracellular Hb level at 1 mM after 1 hr relative to total Hb level | Homo sapiens | 9 | ALA4196122 | cell-based format | Scientific Literature | |
10. | ALA4199830 | P | Aqueous solubility of the compound in DMSO/H2O2 solution at 2.5 mM | 11 | ALA4196122 | small-molecule physicochemical format | Scientific Literature |