# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1776950 | Binding | Competitive inhibition of His-tagged human XIAP BIR3 domain expressed in Escherichia coli BL21(DE3) after 2 to 3 hrs by fluorescence polarization assay | Homo sapiens | 16 | ALA1772970 | assay format | Scientific Literature | |
2. | ALA1776951 | Binding | Binding affinity to His-tagged human XIAP BIR3 domain expressed in Escherichia coli BL21(DE3) after 2 to 3 hrs by fluorescence polarization-based assay | Homo sapiens | 16 | ALA1772970 | assay format | Scientific Literature | |
3. | ALA1776952 | Binding | Competitive inhibition of human XIAP linker BIR2-BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polarization-based assay | Homo sapiens | 16 | ALA1772970 | cell-based format | Scientific Literature | |
4. | ALA1776953 | Binding | Binding affinity to human XIAP linker BIR2-BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polarization-based assay | Homo sapiens | 16 | ALA1772970 | cell-based format | Scientific Literature | |
5. | ALA1777015 | Binding | Competitive inhibition of human cIAP1 BIR3 domain after 2 to 3 hrs by fluorescence polarization assay | Homo sapiens | 16 | ALA1772970 | single protein format | Scientific Literature | |
6. | ALA1777016 | Binding | Binding affinity to human cIAP1 BIR3 domain after 2 to 3 hrs by fluorescence polarization-based assay | Homo sapiens | 16 | ALA1772970 | single protein format | Scientific Literature | |
7. | ALA1777017 | Binding | Competitive inhibition of human cIAP1BIR2-BIR3 domain after 2 to 3 hrs by fluorescence polarization assay | Homo sapiens | 16 | ALA1772970 | single protein format | Scientific Literature | |
8. | ALA1777018 | Binding | Binding affinity to human cIAP1 BIR2-BIR3 domain after 2 to 3 hrs by fluorescence polarization-based assay | Homo sapiens | 16 | ALA1772970 | single protein format | Scientific Literature | |
9. | ALA1777139 | Binding | Competitive inhibition of human cIAP2 BIR3 domain after 2 to 3 hrs by fluorescence polarization assay | Homo sapiens | 16 | ALA1772970 | single protein format | Scientific Literature | |
10. | ALA1777140 | Binding | Binding affinity to human cIAP2 BIR3 domain after 2 to 3 hrs by fluorescence polarization-based assay | Homo sapiens | 16 | ALA1772970 | single protein format | Scientific Literature | |
11. | ALA1777141 | Functional | Growth inhibition of human MDA-MB-231 cells after 2 to 3 hrs by WST8 assay | Homo sapiens | 16 | ALA1772970 | cell-based format | Scientific Literature | |
12. | ALA1777204 | Functional | Antagonist activity at human XIAP linker BIR2-BIR3 domain assessed as restoration of caspase 9 activity at 1.5 uM preincubated for 15 mins using Z-LEHD substrate by caspase-Glo 9 assay | Homo sapiens | 10 | ALA1772970 | assay format | Scientific Literature |