#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA1777159	B	Inhibition of human recombinant mTOR expressed in insect cells using 4E-BP1 substrate after 30 mins by fluorescence resonance energy transfer assay	Homo sapiens	35	ALA1773044	cell-based format	Scientific Literature
2.	ALA1777160	A	Clearance in mouse at 1 mg/kg, iv	Mus musculus	12	ALA1773044	organism-based format	Scientific Literature
3.	ALA1777161	F	Antiproliferative activity against human MCF7 cells expressing neo/Her2 after 3 days by CellTiter-Glo luminescent cell viability assay	Homo sapiens	31	ALA1773044	cell-based format	Scientific Literature
4.	ALA1777162	F	Antiproliferative activity against human PC3 cells after 3 days by CellTiter-Glo luminescent cell viability assay	Homo sapiens	31	ALA1773044	cell-based format	Scientific Literature
5.	ALA1777163	B	Inhibition of mTOR in human NCI-PC3 cells assessed as inhibition of p70S6k phosphorylation by electrochemiluminescence assay	Homo sapiens	31	ALA1773044	cell-based format	Scientific Literature
6.	ALA1777164	B	Selectivity for Ki for human recombinant mTOR (1360-2549) over Ki for PI3Kdelta		31	ALA1773044	assay format	Scientific Literature
7.	ALA1777165	B	Inhibition of mTor in human NCI-PC3 cells assessed as inhibition of Akt phosphorylation at serine473 by electrochemiluminescence assay	Homo sapiens	31	ALA1773044	cell-based format	Scientific Literature
8.	ALA1777166	B	Selectivity ratio of Ki for human recombinant mTOR (1360-2549) over Ki for PI3Kalpha		35	ALA1773044	assay format	Scientific Literature
9.	ALA1777167	A	Volume of distribution at steady state in mouse at 1 mg/kg, iv	Mus musculus	12	ALA1773044	organism-based format	Scientific Literature
10.	ALA1777168	A	Half life in mouse at 1 mg/kg, iv	Mus musculus	12	ALA1773044	organism-based format	Scientific Literature
11.	ALA1777169	A	AUC in mouse at 5 mg/kg, po	Mus musculus	12	ALA1773044	organism-based format	Scientific Literature
12.	ALA1777170	A	Oral bioavailability in mouse at 5 mg/kg	Mus musculus	12	ALA1773044	organism-based format	Scientific Literature
13.	ALA1777171	A	Plasma protein binding in human	Homo sapiens	12	ALA1773044	cell-free format	Scientific Literature
14.	ALA1777172	A	Plasma protein binding in rat	Rattus norvegicus	12	ALA1773044	cell-free format	Scientific Literature
15.	ALA1777173	A	Plasma protein binding in mouse	Mus musculus	12	ALA1773044	cell-free format	Scientific Literature
16.	ALA1777174	F	In vivo inhibition of mTORC1 in po dosed NCR nude mouse xenografted with human NCI-PC3 cells assessed as reduction in phosphorylated S6RP level after 10 hrs	Mus musculus	2	ALA1773044	organism-based format	Scientific Literature
17.	ALA1777175	F	In vivo inhibition of mTORC1 in NCR nude mouse xenografted with human NCI-PC3 cells assessed as reduction in phosphorylated S6RP level at 25 to 100 mg/kg, po administered as single dose relative to control	Mus musculus	2	ALA1773044	organism-based format	Scientific Literature
18.	ALA1777176	F	In vivo inhibition of mTORC2 in po dosed NCR nude mouse xenografted with human NCI-PC3 cells assessed as reduction in phosphorylated Akt level after 10 hrs	Mus musculus	2	ALA1773044	organism-based format	Scientific Literature
19.	ALA1777177	F	In vivo inhibition of mTORC2 in NCR nude mouse xenografted with human NCI-PC3 cells assessed as reduction in phosphorylated Akt level at 25 to 100 mg/kg, po administered as single dose relative to control	Mus musculus	2	ALA1773044	organism-based format	Scientific Literature