| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1775250 | B | Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO-K1 cells after 60 mins by scintillation counting | Homo sapiens | 21 | ALA1772991 | cell-based format | Scientific Literature | |
| 2. | ALA1775251 | A | Permeability from apical to basolateral side of human Caco2 cells after 120 mins | Homo sapiens | 19 | ALA1772991 | cell-based format | Scientific Literature | |
| 3. | ALA1775252 | F | In vivo antihistaminic activity at histamine H1 receptor in ddY mouse assessed as inhibition of histamine-induced skin vascular permeability at 3 mg/kg, po administered 1 hr before histamine challenge by Evan's blue staining | Mus musculus | 6 | ALA1772991 | organism-based format | Scientific Literature | |
| 4. | ALA1775253 | A | Oral bioavailability in fasted rat at 10 mg/kg after 24 hrs | Rattus norvegicus | 5 | ALA1772991 | organism-based format | Scientific Literature | |
| 5. | ALA1775254 | F | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse biphasic allergic model assessed as immediate type reaction at 10 mg/kg, po administered 1 hr before ovalbumin challenge measured 1 hr after elicitation by ear swelling assay | Mus musculus | 6 | ALA1772991 | organism-based format | Scientific Literature | |
| 6. | ALA1775255 | F | Antiinflammatory activity in ovalbumin-sensitized BALB/c mouse biphasic allergic model assessed as late type reaction at 10 mg/kg, po administered 1 hr before ovalbumin challenge measured 24 hrs after elicitation by ear swelling assay | Mus musculus | 6 | ALA1772991 | organism-based format | Scientific Literature | |
| 7. | ALA1775423 | B | Displacement of [3H]prazosin from human adrenergic alpha1 expressed in CHO-K1 cells after 30 mins by scintillation counting | Homo sapiens | 3 | ALA1772991 | cell-based format | Scientific Literature | |
| 8. | ALA1775424 | B | Ratio of IC50 for human adrenergic alpha1 to IC50 for human histamine H1 receptor | Homo sapiens | 3 | ALA1772991 | assay format | Scientific Literature | |
| 9. | ALA1775426 | F | Ex vivo receptor occupancy of histamine H1 receptor in mouse brain at ED70 after 30 mins by scintillation counting | Mus musculus | 4 | ALA1772991 | organism-based format | Scientific Literature |
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