The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
The page will load shortly, Thanks for your patience!
# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA1776795 F Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay Mus musculus 21 cell-based format Scientific Literature 2. ALA1776796 F Antagonist activity at chimpanzee P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay Pan troglodytes 21 cell-based format Scientific Literature 3. ALA1776797 B Displacement of [3H]-UDP from chimpanzee P2Y14 receptor expressed in HEK293 cells Pan troglodytes 20 cell-based format Scientific Literature 4. ALA1776798 A Drug metabolism in Mrp2 (-/-) mouse assessed as (2S,3S,4S,5R,6S)-6-(7-(4-fluoro-2,6-dimethylbenzyloxy)-4-(thiophen-3-yl)-2-naphthoyloxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid recovery in bile at 2 mg/kg, po up to 72 hrs Mus musculus 1 organism-based format Scientific Literature 5. ALA1776799 A Metabolic stability in C57BL/6 mouse Hepatocyte assessed as parent compound remaining at 20 uM after 2 hrs Mus musculus 7 cell-based format Scientific Literature 6. ALA1776800 A Oral bioavailability in C57BL/6 mouse at 50 mg/kg, po administered in 5% Tween-80 Mus musculus 6 organism-based format Scientific Literature 7. ALA1776802 A Intrinsic clearance in C57BL/6 mouse at 2 mg/kg, iv administered in 60% PEG-200 Mus musculus 7 organism-based format Scientific Literature 8. ALA1776803 A Half life in C57BL/6 mouse at 50 mg/kg, po and 2 mg/kg, iv Mus musculus 7 organism-based format Scientific Literature 9. ALA1776859 A Cmax in C57BL/6 mouse at 50 mg/kg, po administered in 5% Tween-80 Mus musculus 6 organism-based format Scientific Literature 10. ALA5257775 A Oral bioavailability in C57BL/6 mouse at 50 mg/kg Mus musculus 1 organism-based format Scientific Literature 11. ALA5257776 A Half life in C57BL/6 mouse 50 mg/kg, iv Mus musculus 1 organism-based format Scientific Literature 12. ALA5257777 A Half life in C57BL/6 mouse 2 mg/kg, iv Mus musculus 1 organism-based format Scientific Literature 13. ALA5257778 A Oral bioavailability in C57BL/6 mouse at 2 mg/kg Mus musculus 1 organism-based format Scientific Literature 14. ALA3721017 F Antagonist activity against chimpanzee GPR105 expressed in stable HEK cells co-expressing chimeric G-protein Gqi5 assessed as inhibition of UDP-glucose-induced Ca2+ signaling response incubated for 20 mins by FLIPR assay Pan troglodytes 40 cell-based format Patent Bioactivity Data 15. ALA4349431 B Inhibition of mouse P2Y14 receptor Mus musculus 2 single protein format Scientific Literature 16. ALA4349432 B Inhibition of chimpanzee P2Y14 receptor Pan troglodytes 2 assay format Scientific Literature