# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1776795 | F | Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Mus musculus | 21 | cell-based format | Scientific Literature | ||
2. | ALA1776796 | F | Antagonist activity at chimpanzee P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Pan troglodytes | 21 | cell-based format | Scientific Literature | ||
3. | ALA1776797 | B | Displacement of [3H]-UDP from chimpanzee P2Y14 receptor expressed in HEK293 cells | Pan troglodytes | 20 | cell-based format | Scientific Literature | ||
4. | ALA1776799 | A | Metabolic stability in C57BL/6 mouse Hepatocyte assessed as parent compound remaining at 20 uM after 2 hrs | Mus musculus | 7 | cell-based format | Scientific Literature | ||
5. | ALA1776800 | A | Oral bioavailability in C57BL/6 mouse at 50 mg/kg, po administered in 5% Tween-80 | Mus musculus | 6 | organism-based format | Scientific Literature | ||
6. | ALA1776802 | A | Intrinsic clearance in C57BL/6 mouse at 2 mg/kg, iv administered in 60% PEG-200 | Mus musculus | 7 | organism-based format | Scientific Literature | ||
7. | ALA1776803 | A | Half life in C57BL/6 mouse at 50 mg/kg, po and 2 mg/kg, iv | Mus musculus | 7 | organism-based format | Scientific Literature | ||
8. | ALA1776859 | A | Cmax in C57BL/6 mouse at 50 mg/kg, po administered in 5% Tween-80 | Mus musculus | 6 | organism-based format | Scientific Literature |