# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1777498 | B | Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-dUTP incorporation into DNA strand by rapid plate assay | Vaccinia virus | 28 | ALA1773050 | single protein format | Scientific Literature | |
2. | ALA1777499 | A | Cytotoxicity against african green monkey BSC1 cells infected with Vaccinia virus assessed as lactate dehydrogenase release after 20 hrs by microplate reader | Chlorocebus aethiops | 28 | ALA1773050 | cell-based format | Scientific Literature | |
3. | ALA1777500 | B | Binding affinity at Vaccinia virus WR strain D4 assessed as change in unfolding transition temperature at 50 uM by thermofluor method | Vaccinia virus WR | 27 | ALA1773050 | single protein format | Scientific Literature | |
4. | ALA1777502 | F | Antiviral activity against Vaccinia virus infected in BSC-1 cells by plaque reduction assay | Vaccinia virus | 28 | ALA1773050 | organism-based format | Scientific Literature | |
5. | ALA1777503 | T | Selectivity index, CC50 for African green monkey BSC-1 cells to EC50 for Vaccinia virus | 22 | ALA1773050 | cell-based format | Scientific Literature | ||
6. | ALA1777504 | B | Binding affinity at Vaccinia virus WR strain D4 assessed as melting temperature at 50 uM by thermofluor method (Rvb = 38.4 +/- 1.6 degC) | Vaccinia virus WR | 27 | ALA1773050 | single protein format | Scientific Literature |