# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA666660 | B | Inhibitory activity against isolated chicken liver dihydrofolate reductase (DHFR) | Gallus gallus | 75 | ALA1122558 | assay format | Scientific Literature | |
2. | ALA664886 | B | Inhibition of Escherichia coli dihydrofolate reductase. | 32 | ALA1122876 | single protein format | Scientific Literature | ||
3. | ALA669613 | B | Inhibitory activity against dihydrofolate reductase isolated from murine L5178Y tumor cells resistant to methotrexate. | 35 | ALA1122587 | cell-based format | Scientific Literature | ||
4. | ALA669614 | B | Inhibitory activity against dihydrofolate reductase (DHFR) isolated from murine L5178Y tumor cells resistant and sensitive to methotrexate | 109 | ALA1122587 | cell-based format | Scientific Literature | ||
5. | ALA667186 | B | Inhibition constant against binding of Escherichia coli dihydrofolate reductase | Escherichia coli | 72 | ALA1124156 | single protein format | Scientific Literature | |
6. | ALA667809 | B | Binding affinity for dihydrofolate reductase from Lactobacillus casei | Lacticaseibacillus casei | 47 | ALA1130169 | single protein format | Scientific Literature | |
7. | ALA857514 | B | Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR) | Lacticaseibacillus casei | 44 | ALA1121755 | single protein format | Scientific Literature | |
8. | ALA668388 | B | Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR) | Lacticaseibacillus casei | 75 | ALA1122558 | single protein format | Scientific Literature | |
9. | ALA666235 | B | The concentration required to inhibit dihydrofolate reductase in rat liver | 107 | ALA1122689 | tissue-based format | Scientific Literature | ||
10. | ALA666237 | B | Inhibition of dihydrofolate reductase | 36 | ALA1122259 | single protein format | Scientific Literature | ||
11. | ALA704963 | F | Inhibitory activity against methotrexate- resistant Lactobacillus casei cells | Lacticaseibacillus casei | 32 | ALA1121755 | organism-based format | Scientific Literature | |
12. | ALA704964 | F | Inhibitory activity against methotrexate- sensitive Lactobacillus casei cells | Lacticaseibacillus casei | 41 | ALA1121755 | organism-based format | Scientific Literature | |
13. | ALA858248 | F | Concentration required for inhibition of murine leukemia L5178Y cells | Mus musculus | 42 | ALA1122006 | cell-based format | Scientific Literature | |
14. | ALA707335 | F | Compound was tested in vitro for concentration required to decrease 50% growth rate of murine leukemia L5178Y/R cell culture | Mus musculus | 46 | ALA1122007 | cell-based format | Scientific Literature | |
15. | ALA4054609 | F | Antiviral activity against Respiratory syncytial virus infected in human HeLa cells assessed as inhibition of viral-induced cytopathic effect measured after 3 to 6 days post infection by microscopic analysis | Respiratory syncytial virus | 34 | ALA4052640 | cell-based format | Scientific Literature | |
16. | ALA4054613 | F | Antiviral activity against Yellow fever virus infected in African green monkey Vero cells assessed as inhibition of viral-induced cytopathic effect measured after 3 to 6 days post infection by microscopic analysis | Yellow fever virus | 35 | ALA4052640 | assay format | Scientific Literature | |
17. | ALA4054614 | F | Antiviral activity against Punta Toro virus infected in African green monkey Vero cells assessed as inhibition of viral-induced cytopathic effect measured after 3 to 6 days post infection by microscopic analysis | Punta Toro virus | 35 | ALA4052640 | assay format | Scientific Literature | |
18. | ALA4054615 | F | Antiviral activity against Coxsackie B4 virus infected in African green monkey Vero cells assessed as inhibition of viral-induced cytopathic effect measured after 3 to 6 days post infection by microscopic analysis | Coxsackievirus B4 | 35 | ALA4052640 | assay format | Scientific Literature | |
19. | ALA4054616 | F | Antiviral activity against Sindbis virus infected in African green monkey Vero cells assessed as inhibition of viral-induced cytopathic effect measured after 3 to 6 days post infection by microscopic analysis | Sindbis virus | 35 | ALA4052640 | assay format | Scientific Literature | |
20. | ALA4054617 | F | Antiviral activity against Reovirus 1 infected in African green monkey Vero cells assessed as inhibition of viral-induced cytopathic effect measured after 3 to 6 days post infection by microscopic analysis | Mammalian orthoreovirus 1 | 35 | ALA4052640 | assay format | Scientific Literature |