| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1781817 | B | Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liquid scintillation counting | 9 | single protein format | Scientific Literature | |||
| 2. | ALA1781818 | A | Stability in human liver microsomes assessed as compound remaining after 60 mins | Homo sapiens | 9 | microsome format | Scientific Literature | ||
| 3. | ALA1780631 | F | In vivo inhibition of squalene synthase in NMRI rat assessed as inhibition of hepatic [14C]cholesterol biosynthesis at 3 mg/kg, po measured after 1 hr by liquid scintillation counting | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 4. | ALA1780632 | F | In vivo inhibition of squalene synthase in NMRI rat assessed as inhibition of hepatic [14C]cholesterol biosynthesis at 1 mg/kg, po measured after 1 hr by liquid scintillation counting | Rattus norvegicus | 9 | organism-based format | Scientific Literature |
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