| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1781474 | F | Antiviral activity against Hepatitis B virus infected in human HepG2(2.2.15) cells assessed as inhibition of viral DNA replication after 4 days by RT-PCR analysis | Hepatitis B virus | 36 | organism-based format | Scientific Literature | ||
| 2. | ALA1781475 | A | Cytotoxicity against human HepG2(2.2.15) cells after 8 days by MTT assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 3. | ALA1781476 | F | Selectivity index, ratio of CC50 for human HepG2.2.15 cells to IC50 for Hepatitis B virus | 36 | assay format | Scientific Literature | |||
| 4. | ALA5253430 | B | Modulation of TRPV1 (unknown origin) by fluorometric imaging plate reader analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA5253448 | B | Antagonist activity at TRPM8 (unknown origin) | Homo sapiens | 16 | single protein format | Scientific Literature | ||
| 6. | ALA3791378 | B | Antagonist activity at mouse TRPM8 expressed in HEK293 cells assessed as inhibition of menthol mediated calcium flux at 0.5 to 50 preincubated for 60 mins followed by menthol addition by Fluo-4 NW dye based fluorometric assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
| 7. | ALA3791380 | B | Antagonist activity at mouse TRPV1 stably expressed in human SH-SY5Y cells assessed as inhibition of capsaicin mediated calcium flux at 50 uM preincubated for 60 mins followed by capsaicin addition by Fluo-4 NW dye based fluorometric assay in presence of ruthenium dye | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA3791382 | B | Antagonist activity at mouse TRPA1 natively expressed in human IMR90 cells assessed as inhibition of AITC mediated calcium flux at 0.5 to 50 uM preincubated for 60 mins followed by AITC addition by Fluo-4 NW dye based fluorometric assay in presence of ruthenium dye | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA3791386 | B | Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of menthol mediated current amplitude at +80 mV holding potential by whole cell patch-clamp assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA3791387 | B | Agonist activity at rat TRPM8 expressed in HEK293 cells assessed as appearance of large outwardly rectifying currents at 100 uM at +80 mV holding potential by whole cell patch-clamp assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA3791388 | B | Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of menthol mediated current amplitude at 3 uM at +80 mV holding potential by whole cell patch-clamp assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA3791389 | B | Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of menthol mediated current amplitude at 3 uM at +80 mV holding potential measured after drug wash out by whole cell patch-clamp assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4256797 | B | Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as reduction in menthol-induced calcium flux incubated for 60 mins by Fluo-4 NW-dye based fluorimetric assay | Rattus norvegicus | 13 | cell-based format | Scientific Literature |
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