# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1788041 | B | Inhibition of Manduca sexta V-ATPase V1/Vo holoenzyme activity assessed as inorganic phosphate production pretreated for 5 mins | Manduca sexta | 6 | single protein format | Scientific Literature | ||
2. | ALA1788042 | F | Antiproliferative activity against mouse L929 cells assessed as growth inhibition after 5 days by MTT assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
3. | ALA1788043 | F | Antiproliferative activity against human KB-3-1 cells after 5 days by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA1788044 | F | Antiproliferative activity against human U937 cells after 5 days by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA1788045 | F | Antiproliferative activity against human SKOV3 cells after 5 days by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA1788046 | F | Antiproliferative activity against human A431 cells after 5 days by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA1788047 | F | Antiproliferative activity against human PC3 cells after 5 days by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA1788048 | F | Antiproliferative activity against human MCF7 cells after 5 days by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA4381886 | A | Intrinsic clearance in CD1 mouse liver microsomes at 1 uM | Mus musculus | 2 | microsome format | Scientific Literature | ||
10. | ALA4381889 | F | Growth inhibition of human 1321N1 cells incubated for 72 hrs by MTT assay | Homo sapiens | 9 | assay format | Scientific Literature | ||
11. | ALA4381890 | B | Inhibition of Manduca sexta V-type proton ATPase assessed as reduction in inorganic phosphate production pre-inucubated for 5 mins before Tris-ATP addition and measured after 2 mins | Manduca sexta | 8 | assay format | Scientific Literature | ||
12. | ALA4381891 | B | Inhibition of human P2X3 assessed as reduction in agonist-induced intracellular Ca2+ concentration pre-incubated for 30 mins before agonist addition by calcium 5 dye based fluorescence assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
13. | ALA4381892 | B | Displacement of [3H]PSB-11 from human A3 adenosine receptor expressed in CHO cell membranes incubated for 60 mins by liquid scintillation counting method | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
14. | ALA4381893 | B | Inhibition of human leukocyte elastase assessed as reduction in pNA release using chromogenic MeO-Suc-Ala-Ala-Pro-Val-pNA substrate measured over 10 mins by spectrophotometry | Homo sapiens | 9 | single protein format | Scientific Literature | ||
15. | ALA4381914 | B | Inhibition of trypsin (unknown origin) assessed as reduction in pNA release using chromogenic Suc-Ala-Ala-Pro-Arg-pNA substrate measured over 10 mins by spectrophotometry | Homo sapiens | 3 | protein format | Scientific Literature | ||
16. | ALA4381915 | B | Inhibition of cathepsin B (unknown origin) assessed as reduction in pNA release using chromogenic Z-Arg-Arg-pNA substrate measured over 1 hr by spectrophotometry | Homo sapiens | 3 | single protein format | Scientific Literature | ||
17. | ALA4381916 | B | Inhibition of cathepsin L (unknown origin) assessed as reduction in pNA release using chromogenic Z-Phe-Arg-pNA substrate measured over 1 hr by spectrophotometry | Homo sapiens | 3 | single protein format | Scientific Literature | ||
18. | ALA4381917 | B | Inhibition of chymotrypsin (unknown origin) assessed as reduction in pNA release using chromogenic Suc-Ala-Ala-Pro-Phe-pNA substrate measured over 12.5 mins by spectrophotometry | Homo sapiens | 3 | protein format | Scientific Literature | ||
19. | ALA4381925 | A | Stability in CD1 mouse liver microsomes assessed as rapid demethylation at 1 uM | Mus musculus | 1 | microsome format | Scientific Literature | ||
20. | ALA4381926 | A | Stability in CD1 mouse liver microsomes assessed as rapid oxidation at 1 uM | Mus musculus | 1 | microsome format | Scientific Literature |