#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA1785541	B	Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as substrate after 10 to 15 mins by DCIP dye-based assay	Plasmodium falciparum	59		assay format	Scientific Literature
2.	ALA1785542	B	Inhibition of His6-tagged recombinant Plasmodium berghei dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as substrate after 10 to 15 mins by DCIP dye-based assay	Plasmodium berghei	59		assay format	Scientific Literature
3.	ALA1785543	B	Inhibition of His6-tagged recombinant human dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as substrate after 10 to 15 mins by DCIP dye-based assay	Homo sapiens	59		assay format	Scientific Literature
4.	ALA1785544	F	Antimalarial activity against Plasmodium falciparum 3D7 infected in human A positive erythrocytes by [3H]hypoxanthine uptake assay in presence of serum in medium	Plasmodium falciparum	62		organism-based format	Scientific Literature
5.	ALA1785545	F	Antimalarial activity against Plasmodium falciparum 3D7 infected in human A positive erythrocytes by [3H]hypoxanthine uptake assay in presence of serum in medium albumax	Plasmodium falciparum	3		organism-based format	Scientific Literature
6.	ALA1785546	U	Ratio of EC50 for Plasmodium falciparum 3D7 in presence of serum in medium to IC50 for His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase	Plasmodium falciparum	2		assay format	Scientific Literature
7.	ALA1785548	P	Partition coefficient, log D of the compound at pH 7.4 by UV-HPLC analysis		21		small-molecule physicochemical format	Scientific Literature
8.	ALA1785549	P	Aqueous solubility of the compound in phosphate buffer at pH 6.5		21		small-molecule physicochemical format	Scientific Literature
9.	ALA1785550	A	Plasma protein binding in human by albumin chromatographic method	Homo sapiens	24		cell-free format	Scientific Literature
10.	ALA1785551	A	Intrinsic clearance in human liver microsome assessed per mg of protein at 1 uM after 60 mins by LC-MS analysis	Homo sapiens	21		microsome format	Scientific Literature
11.	ALA1785552	A	Intrinsic clearance in mouse liver microsome assessed per mg of protein at 1 uM after 60 mins by LC-MS analysis	Mus musculus	19		microsome format	Scientific Literature
12.	ALA1785553	A	Plasma protein binding in rat by ultracentrifugation analysis	Rattus norvegicus	2		cell-free format	Scientific Literature
13.	ALA1785554	A	Cmax in Swiss mouse at 20 mg/kg, po measured after 24 hrs by LC-MS analysis	Mus musculus	8		organism-based format	Scientific Literature
14.	ALA1785555	A	Time duration above 1 uM plasma concentration in Swiss mouse at 20 mg/kg, po	Mus musculus	8		organism-based format	Scientific Literature
15.	ALA1785556	T	Toxicity in Swiss mouse assessed as adverse effect at 20 mg/kg, po measured after 24 hrs	Mus musculus	8		organism-based format	Scientific Literature
16.	ALA1785559	A	Clearance in Sprague-Dawley rat at 0.9 mg/kg, iv by LC-MS analysis	Rattus norvegicus	1		organism-based format	Scientific Literature
17.	ALA1785719	A	Clearance in Sprague-Dawley rat at 2.9 mg/kg, iv by LC-MS analysis	Rattus norvegicus	1		organism-based format	Scientific Literature
18.	ALA1785722	A	Volume of distribution at steady state in Sprague-Dawley rat at 0.9 mg/kg, iv by LC-MS analysis	Rattus norvegicus	1		organism-based format	Scientific Literature
19.	ALA1785723	A	Volume of distribution at steady state in Sprague-Dawley rat at 2.9 mg/kg, iv by LC-MS analysis	Rattus norvegicus	1		organism-based format	Scientific Literature
20.	ALA1785726	A	Terminal elimination half life in Sprague-Dawley rat at 0.9 mg/kg, iv by LC-MS analysis	Rattus norvegicus	1		organism-based format	Scientific Literature