# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1804486 | Binding | Inhibition of SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion at 50 uM after 5 mins by spectrophotometry | 35 | ALA1800013 | single protein format | Scientific Literature | ||
2. | ALA1804487 | Binding | Inhibition of SHP1 | 3 | ALA1800013 | single protein format | Scientific Literature | ||
3. | ALA1804488 | Binding | Inhibition of PTP1B | 3 | ALA1800013 | single protein format | Scientific Literature | ||
4. | ALA1804489 | Binding | Inhibition of SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion after 5 mins by spectrophotometry | 5 | ALA1800013 | single protein format | Scientific Literature | ||
5. | ALA1804491 | Binding | Competitive inhibition at SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion by spectrophotometry | 1 | ALA1800013 | single protein format | Scientific Literature | ||
6. | ALA1804492 | Binding | Reversible inhibition at SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion by spectrophotometry | 1 | ALA1800013 | single protein format | Scientific Literature | ||
7. | ALA1804493 | Binding | Selectivity ratio of IC50 for SHP1 to IC50 for SHP2 catalytic domain | 1 | ALA1800013 | assay format | Scientific Literature | ||
8. | ALA1804494 | Binding | Selectivity ratio of IC50 for PTP1B to IC50 for SHP2 catalytic domain | 1 | ALA1800013 | assay format | Scientific Literature | ||
9. | ALA1804495 | Binding | Inhibition of SHP2 K364R mutant | Homo sapiens | 1 | ALA1800013 | assay format | Scientific Literature | |
10. | ALA1804496 | Binding | Inhibition of SHP2 K364S mutant | Homo sapiens | 1 | ALA1800013 | assay format | Scientific Literature | |
11. | ALA1804497 | Binding | Selectivity ratio of IC50 for SHP2 K364R mutant to IC50 for wild type SHP2 | 1 | ALA1800013 | assay format | Scientific Literature | ||
12. | ALA1804498 | Binding | Selectivity ratio of IC50 for SHP2 K364S mutant to IC50 for wild type SHP2 | 1 | ALA1800013 | assay format | Scientific Literature | ||
13. | ALA1804499 | Binding | Inhibition of TC-PTP | 1 | ALA1800013 | single protein format | Scientific Literature | ||
14. | ALA1804500 | Binding | Inhibition of CD45 | 1 | ALA1800013 | single protein format | Scientific Literature | ||
15. | ALA1804669 | Binding | Inhibition of LAR | 1 | ALA1800013 | single protein format | Scientific Literature | ||
16. | ALA1804670 | Binding | Inhibition of VHX | 1 | ALA1800013 | single protein format | Scientific Literature | ||
17. | ALA1804671 | Binding | Inhibition of LMW-PTP | 1 | ALA1800013 | single protein format | Scientific Literature | ||
18. | ALA1804672 | Binding | Inhibition of LYP at 100 uM | 1 | ALA1800013 | single protein format | Scientific Literature | ||
19. | ALA1804673 | Binding | Inhibition of PTPalpha at 100 uM | 1 | ALA1800013 | single protein format | Scientific Literature | ||
20. | ALA1804674 | Binding | Inhibition of VHR at 100 uM | 1 | ALA1800013 | single protein format | Scientific Literature |