# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1805646 | Functional | Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay | Homo sapiens | 38 | ALA1799938 | cell-based format | Scientific Literature | |
2. | ALA1805647 | Functional | Growth inhibition of human A549 cells after 72 hrs by alamar blue method | Homo sapiens | 4 | ALA1799938 | cell-based format | Scientific Literature | |
3. | ALA1805648 | Functional | Growth inhibition of human NCI-H1944 cells after 72 hrs by alamar blue method | Homo sapiens | 4 | ALA1799938 | cell-based format | Scientific Literature | |
4. | ALA1805649 | Functional | Growth inhibition of human H460 cells after 72 hrs by alamar blue method | Homo sapiens | 4 | ALA1799938 | cell-based format | Scientific Literature | |
5. | ALA1805650 | Functional | Growth inhibition of human NCI-H157 cells after 72 hrs by alamar blue method | Homo sapiens | 4 | ALA1799938 | cell-based format | Scientific Literature | |
6. | ALA1805651 | Binding | Inhibition of TNF-alpha-induced NFkappaB nuclear translocation in human A549 cells preincubated for 30 mins before TNFalpha challenge and measured 30 post TNFalpha challenge by fluorescence method | Homo sapiens | 38 | ALA1799938 | cell-based format | Scientific Literature | |
7. | ALA1805652 | Binding | Inhibition of IKK in human A549 cells assessed as inhibition of TNF-alpha-induced IkappaB phosphorylation preincubated for 30 mins before TNFalpha challenge | Homo sapiens | 3 | ALA1799938 | cell-based format | Scientific Literature | |
8. | ALA1805653 | Binding | Inhibition of IKK in human A549 cells assessed as inhibition of TNF-alpha-induced IkappaB degradation at 0.5 to 25 uM preincubated for 4 hrs before TNFalpha challenge measured after 20 mins by Western blot analysis | Homo sapiens | 3 | ALA1799938 | cell-based format | Scientific Literature | |
9. | ALA1805654 | Binding | Inhibition of recombinant IKK-beta assessed as inhibition of incorporation of [gamma32P] to GST-IkappaBalpha after 30 mins by scintillation counting | 3 | ALA1799938 | single protein format | Scientific Literature | ||
10. | ALA1805655 | Functional | Anticlonogenic activity against human A549 cells assessed as inhibition of colony formation of cells treated at 0.2 uM with test compound after cell plating and every 3 days thereafter and measured on day 9 after colonies formed by SRB assay | Homo sapiens | 2 | ALA1799938 | cell-based format | Scientific Literature |