| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1805779 | B | Inhibition of human platelet cPLA2alpha assessed as inhibition of arachidonic acid production after 60 mins by UV-reverse phase HPLC analysis | Homo sapiens | 21 | ALA1799943 | assay format | Scientific Literature | |
| 2. | ALA1805780 | A | Metabolic stability in rat liver microsomes assessed as compound remaining after 30 mins by UV-reverse phase HPLC analysis | Rattus norvegicus | 20 | ALA1799943 | microsome format | Scientific Literature | |
| 3. | ALA1805781 | P | Thermodynamic solubility of the compound in phosphate buffer of pH 7.4 incubated for 20 hrs at room temperature by UV-reverse phase HPLC analysis | 20 | ALA1799943 | small-molecule physicochemical format | Scientific Literature | ||
| 4. | ALA1805782 | P | Partition coefficient, log P of the compound by reverse phase HPLC analysis | 21 | ALA1799943 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA4000775 | A | Metabolic stability in CD-1 mouse liver S9 fraction assessed as UGT-mediated glucuronidation of compound by measuring compound remaining at 5 uM preincubated for 3 mins followed by UDPGA addition measured after 60 mins by HPLC/MS analysis | Mus musculus | 12 | ALA4000171 | assay format | Scientific Literature | |
| 6. | ALA4000776 | A | Metabolic stability in CD-1 mouse liver S9 fraction assessed as NADPH CYP450 reductase-mediated compound metabolism by measuring compound remaining in presence of NADPH at 20 uM after 30 mins by HPLC method | Mus musculus | 11 | ALA4000171 | assay format | Scientific Literature | |
| 7. | ALA4000777 | P | Thermodynamic solubility of the compound in phosphate buffer at pH 7.4 at 1 mg sonicated for 10 mins measured after 20 hrs by reverse phase HPLC analysis | 12 | ALA4000171 | small-molecule physicochemical format | Scientific Literature | ||
| 8. | ALA4000778 | B | Inhibition of human platelet cytosolic phospholipase alpha-2 using 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycerol as substrate after 60 mins by UV-HPLC method | Homo sapiens | 12 | ALA4000171 | assay format | Scientific Literature | |
| 9. | ALA4000779 | A | Metabolic stability in rat liver microsomes assessed as NADPH CYP450 reductase-mediated compound metabolism by measuring compound remaining in presence of NADPH at 20 uM after 30 mins by HPLC | Rattus norvegicus | 11 | ALA4000171 | assay format | Scientific Literature | |
| 10. | ALA4000780 | A | Metabolic stability in rat liver S9 fraction assessed as NADPH CYP450 reductase-mediated compound metabolism by measuring compound remaining in presence of NADPH at 20 uM after 30 mins by HPLC method | Rattus norvegicus | 11 | ALA4000171 | assay format | Scientific Literature | |
| 11. | ALA4000781 | A | Metabolic stability in Wistar rat liver S9 fraction assessed as UGT-mediated glucuronidation of compound by measuring compound remaining at 5 uM preincubated for 3 mins followed by UDPGA addition measured after 60 mins by HPLC/MS analysis | Rattus norvegicus | 12 | ALA4000171 | assay format | Scientific Literature |
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