# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3755700 | Functional | Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production at 10 uM in presence of 3 mM extracellular Ca2+ by IP-one assay | Rattus norvegicus | 7 | ALA3751687 | cell-based format | Scientific Literature | |
2. | ALA3755701 | Functional | Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production at 3 uM in presence of 3 mM extracellular Ca2+ by IP-one assay | Rattus norvegicus | 18 | ALA3751687 | cell-based format | Scientific Literature | |
3. | ALA3755702 | Functional | Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production at 10 uM in presence of 2 mM extracellular Ca2+ by IP-one assay | Rattus norvegicus | 10 | ALA3751687 | cell-based format | Scientific Literature | |
4. | ALA3755703 | Functional | Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production at 3 uM in presence of 2 mM extracellular Ca2+ by IP-one assay | Rattus norvegicus | 6 | ALA3751687 | cell-based format | Scientific Literature | |
5. | ALA3755705 | Functional | Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one assay | Rattus norvegicus | 6 | ALA3751687 | cell-based format | Scientific Literature | |
6. | ALA3755706 | Functional | Inhibition of L-Ornithine-stimulated wild type mouse GPRC6A expressed in HEK293 cells coexpressing GalphaqG66D assessed as increase in [3H] inositol phosphate production at 10 uM incubated for 30 mins in presence of 2 mM extracellular Ca2+ | Mus musculus | 4 | ALA3751687 | cell-based format | Scientific Literature | |
7. | ALA1804306 | Functional | Agonist activity at rat CaSR expressed in CHO cells assessed as increase of calcium-induced inositol phosphate accumulation at 10 uM after 24 hrs by HTRF assay relative to calcium | Rattus norvegicus | 10 | ALA1800047 | cell-based format | Scientific Literature | |
8. | ALA1804307 | Functional | Agonist activity at human CaSR E837A mutant expressed in HEK293 cells assessed as increase of calcium-induced inositol phosphate accumulation at 10 uM after 48 hrs by HTRF assay relative to calcium | Homo sapiens | 10 | ALA1800047 | cell-based format | Scientific Literature | |
9. | ALA1804308 | Functional | Agonist activity at human CaSR expressed in HEK293 cells assessed as increase of calcium-induced inositol phosphate accumulation at 10 uM after 48 hrs by HTRF assay relative to calcium | Homo sapiens | 10 | ALA1800047 | cell-based format | Scientific Literature |