# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1804531 | F | Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR assay | Homo sapiens | 34 | ALA1800075 | cell-based format | Scientific Literature | |
2. | ALA1804532 | A | Unbound fraction in rat plasma by ultracentrifugation | Rattus norvegicus | 20 | ALA1800075 | cell-free format | Scientific Literature | |
3. | ALA1804922 | B | Permeability of the compound assessed as rat MDR1-mediated directional transport ratio by cell based assay | Rattus norvegicus | 19 | ALA1800075 | cell-based format | Scientific Literature | |
4. | ALA1804926 | A | AUC (0 to infinity) in rat at 2 mg/kg, po | Rattus norvegicus | 2 | ALA1800075 | organism-based format | Scientific Literature | |
5. | ALA1804927 | A | Drug level in rat cerebrospinal fluid at 75 mg/kg, ip after 30 mins | Rattus norvegicus | 1 | ALA1800075 | organism-based format | Scientific Literature | |
6. | ALA1804928 | A | Drug level in rat cerebrospinal fluid at 75 mg/kg, ip after 2 hrs | Rattus norvegicus | 1 | ALA1800075 | organism-based format | Scientific Literature | |
7. | ALA1804929 | A | Ratio drug level in CSF to plasma in rat at 75 mg/kg, ip | Rattus norvegicus | 1 | ALA1800075 | organism-based format | Scientific Literature | |
8. | ALA1804936 | P | Lipophilicity, log D of the compound by HPLC method | 1 | ALA1800075 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA1804937 | B | Inhibition of thromboxane A2 receptor | 1 | ALA1800075 | single protein format | Scientific Literature | ||
10. | ALA1804938 | B | Inhibition of melatonin receptor | 1 | ALA1800075 | assay format | Scientific Literature | ||
11. | ALA1804939 | B | Inhibition of rabbit monoamine transporter | Oryctolagus cuniculus | 1 | ALA1800075 | assay format | Scientific Literature | |
12. | ALA1804940 | B | Inhibition of sodium channel site 2 | 1 | ALA1800075 | assay format | Scientific Literature |