| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1804603 | F | Antiparasitic activity against Onchocerca ochengi assessed as effect on microfilarial mobility at 5 ug/ml measured every 24 hrs for 120 hrs by inverted microscopic analysis | Onchocerca ochengi | 25 | organism-based format | Scientific Literature | ||
| 2. | ALA1804604 | F | Antiparasitic activity against Onchocerca ochengi assessed as effect on microfilarial mobility at 10 ug/ml measured every 24 hrs for 120 hrs by inverted microscopic analysis | Onchocerca ochengi | 25 | organism-based format | Scientific Literature | ||
| 3. | ALA4270091 | B | Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured MDH refolding after 20 to 40 mins by spectrometric analysis | Escherichia coli | 50 | assay format | Scientific Literature | ||
| 4. | ALA4270092 | B | Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured rhodanese refolding after 45 mins by spectrometric analysis | Escherichia coli | 50 | assay format | Scientific Literature | ||
| 5. | ALA4270093 | F | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 6 to 8 hrs by bacterial proliferation assay | Staphylococcus aureus | 50 | organism-based format | Scientific Literature | ||
| 6. | ALA4270094 | B | Inhibition of refolded rhodanese (unknown origin) preincubated with Escherichia coli GroEL/GroES for 60 mins in absence of compound followed by compound addition by spectrometric analysis | Homo sapiens | 50 | single protein format | Scientific Literature | ||
| 7. | ALA4270095 | B | Inhibition of refolded MDH (unknown origin) preincubated with Escherichia coli GroEL/GroES for 45 mins in absence of compound followed by compound addition and measured for 20 to 35 mins by spectrometric analysis | Homo sapiens | 50 | assay format | Scientific Literature | ||
| 8. | ALA4270096 | F | Antibacterial activity against Enterococcus faecium ATCC 19434 after 24 hrs by bacterial proliferation assay | Enterococcus faecium | 50 | organism-based format | Scientific Literature | ||
| 9. | ALA4270097 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC BAA-44 after 6 to 8 hrs by bacterial proliferation assay | Staphylococcus aureus | 50 | organism-based format | Scientific Literature | ||
| 10. | ALA4270098 | F | Antibacterial activity against Klebsiella pneumoniae ATCC 13883 after 6 to 8 hrs by bacterial proliferation assay | Klebsiella pneumoniae | 50 | organism-based format | Scientific Literature | ||
| 11. | ALA4270099 | F | Antibacterial activity against Acinetobacter baumannii ATCC 19606 after 24 hrs by bacterial proliferation assay | Acinetobacter baumannii | 50 | organism-based format | Scientific Literature | ||
| 12. | ALA4270100 | F | Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 after 24 hrs by bacterial proliferation assay | Pseudomonas aeruginosa | 50 | organism-based format | Scientific Literature | ||
| 13. | ALA4270101 | F | Antibacterial activity against Enterobacter cloacae subsp. cloacae ATCC 13047 after 24 hrs by bacterial proliferation assay | Enterobacter cloacae | 50 | organism-based format | Scientific Literature | ||
| 14. | ALA4270102 | B | Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Rosetta(DE3) assessed as reduction in HSP60/HSP10-mediated denatured MDH refolding after 40 to 60 mins by spectrometric analysis | Homo sapiens | 50 | assay format | Scientific Literature | ||
| 15. | ALA4270103 | A | Cytotoxicity against human THLE3 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue reporter assay | Homo sapiens | 50 | cell-based format | Scientific Literature | ||
| 16. | ALA4270104 | A | Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue reporter assay | Homo sapiens | 50 | cell-based format | Scientific Literature | ||
| 17. | ALA4270110 | T | Therapeutic index, ratio of CC50 for human THLE3 cells to EC50 for methicillin-resistant Staphylococcus aureus ATCC BAA-44 | 4 | assay format | Scientific Literature | |||
| 18. | ALA4270111 | T | Therapeutic index, ratio of CC50 for HEK293 cells to EC50 for methicillin-resistant Staphylococcus aureus ATCC BAA-44 | 4 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!