# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1805065 | B | Competitive inhibition of His-tagged FimH carbohydrate recognizing domain expressed in Escherichia coli HM125 using ABTS-substrate after 3 hrs by calorimetric assay | Escherichia coli | 18 | ALA1799951 | assay format | Scientific Literature | |
2. | ALA1805066 | B | Ratio IC50 for compound to IC50 for n-heptyl R-D-mannopyranoside for His-tagged FimH expressed in Escherichia coli HM125 | Escherichia coli | 18 | ALA1799951 | assay format | Scientific Literature | |
3. | ALA1805067 | F | Antagonist activity at Escherichia coli UT189 FimH in guinea pig red blood cells assessed as disaggregation of bacteria after 600 secs by aggregometry assay | Escherichia coli | 18 | ALA1799951 | cell-based format | Scientific Literature | |
4. | ALA1805239 | P | Dissociation constant, pKa of the compound by NMR spectrometric analysis | 6 | ALA1799951 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA1805240 | P | Lipophilicity, log D at pH 7.4 by miniatured shake flask method | 18 | ALA1799951 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA1805241 | A | Permeability coefficient, log Pe of the compound by PAMPA method | 18 | ALA1799951 | assay format | Scientific Literature | ||
7. | ALA1805242 | A | Permeability of the compound assessed as membrane retention by PAMPA method | 15 | ALA1799951 | assay format | Scientific Literature | ||
8. | ALA1805243 | A | Apparent permeability across human Caco2 cells after 120 mins by HPLC analysis | Homo sapiens | 18 | ALA1799951 | cell-based format | Scientific Literature | |
9. | ALA1805244 | P | Thermodynamic solubility of the compound at pH 6.5 after 24 hrs by LC-MS analysis | 18 | ALA1799951 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA1805250 | A | Plasma protein binding in human by miniatured equilibrium dialysis method | Homo sapiens | 18 | ALA1799951 | cell-free format | Scientific Literature |