| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1811277 | B | Inhibition of human cloned GST-fused p38alpha expressed in Escherichia coli using myelin basic protein as substrate after 45 mins | Homo sapiens | 36 | assay format | Scientific Literature | ||
| 2. | ALA1811278 | F | Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced TNFalpha production treated 30 mins before LPS challenge measured after 6 hrs by ELISA | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 3. | ALA1811281 | A | Clearance in human liver microsomes | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 4. | ALA1811282 | F | Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced IL-1alpha production treated 30 mins before LPS challenge measured after 6 hrs by ELISA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1811283 | F | Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced IL1-beta production treated 30 mins before LPS challenge measured after 6 hrs by ELISA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA1811284 | F | Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced IL-6 production treated 30 mins before LPS challenge measured after 6 hrs by ELISA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA1811285 | F | Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced IL-10 production treated 30 mins before LPS challenge measured after 6 hrs by ELISA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA1811286 | F | Antiinflammatory activity in monkey whole blood assessed as inhibition of LPS-induced IL-6 production | Macaca mulatta | 1 | tissue-based format | Scientific Literature | ||
| 9. | ALA1811287 | F | Antiinflammatory activity in BALB/c mouse assessed as inhibition of LPS-induced TNFalpha production at 5 mg/kg, po administered 2 hrs before LPS challenge measured after 90 mins by ELISA | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 10. | ALA1811288 | F | Antiinflammatory activity in BALB/c mouse assessed as inhibition of LPS-induced TNFalpha production in serum at 5 mg/kg, po administered 6 hrs before LPS challenge measured after 90 mins by ELISA | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA1811289 | B | Inhibition of p38beta | 1 | single protein format | Scientific Literature | |||
| 12. | ALA1811570 | B | Inhibition of p38delta | 1 | single protein format | Scientific Literature | |||
| 13. | ALA1811571 | B | Inhibition of p38-gamma | 1 | single protein format | Scientific Literature | |||
| 14. | ALA1811572 | B | Inhibition of Akt | 1 | single protein format | Scientific Literature | |||
| 15. | ALA1811573 | B | Inhibition of CDK2 | 1 | single protein format | Scientific Literature | |||
| 16. | ALA1811574 | B | Inhibition of EMT | 1 | single protein format | Scientific Literature | |||
| 17. | ALA1811575 | B | Inhibition of FGFR1 | 1 | single protein format | Scientific Literature | |||
| 18. | ALA1811576 | B | Inhibition of HER1 | 1 | single protein format | Scientific Literature | |||
| 19. | ALA1811577 | B | Inhibition of HER2 | 1 | single protein format | Scientific Literature | |||
| 20. | ALA1811578 | B | Inhibition of IGF1R | 1 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!