# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1810317 | Binding | Ex vivo receptor occupancy of CXCR3 in rat blood assessed as inhibition of ITAC binding after 1 hr by flow cytometry | Rattus norvegicus | 9 | ALA1806382 | assay format | Scientific Literature | |
2. | ALA1810318 | Binding | Ex vivo receptor occupancy of CXCR3 in human blood assessed as inhibition of ITAC binding after 1 hr by flow cytometry | Homo sapiens | 3 | ALA1806382 | single protein format | Scientific Literature | |
3. | ALA1810319 | Binding | Displacement of radiolabeled CXCL11 from human CXCR3 expressed in CHO cells by scintillation proximity assay | Homo sapiens | 52 | ALA1806382 | cell-based format | Scientific Literature | |
4. | ALA1810320 | Functional | Antagonist activity at human CXCR3 expressed in mouse L1.2 cells assessed as inhibition of ITAC-induced calcium mobilization by FLIPR assay | Homo sapiens | 52 | ALA1806382 | cell-based format | Scientific Literature | |
5. | ALA1810321 | Functional | Antagonist activity at mouse CXCR3 expressed in mouse L1.2 cells assessed as inhibition of ITAC-induced calcium mobilization by FLIPR assay | Mus musculus | 34 | ALA1806382 | cell-based format | Scientific Literature | |
6. | ALA1810322 | Functional | Antagonist activity at CXCR3 in rat leukocytes assessed as inhibition of ITAC-induced cell migration by flow cytometry | Rattus norvegicus | 4 | ALA1806382 | cell-based format | Scientific Literature | |
7. | ALA1810323 | ADME | Fraction unbound in rat serum | Rattus norvegicus | 3 | ALA1806382 | cell-free format | Scientific Literature | |
8. | ALA1810324 | ADME | Fraction unbound in human serum | Homo sapiens | 3 | ALA1806382 | cell-free format | Scientific Literature |