# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1810427 | F | Antiviral activity against Influenza A virus (A/Aichi/2/68 (H3N2)) virus infected in MDCK cells expressing airway trypsin-like protease HAT assessed as infected cells at 10 uM after 24 hrs by immunostaining in presence of doxycycline relative to control | Influenza A virus | 4 | ALA1806464 | organism-based format | Scientific Literature | |
2. | ALA1810428 | B | Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader analysis | Homo sapiens | 41 | ALA1806464 | single protein format | Scientific Literature | |
3. | ALA1810429 | B | Inhibition of thrombin | 12 | ALA1806464 | single protein format | Scientific Literature | ||
4. | ALA1810430 | B | Inhibition of factor 10a | 12 | ALA1806464 | single protein format | Scientific Literature | ||
5. | ALA1810431 | B | Inhibition of plasmin | 12 | ALA1806464 | single protein format | Scientific Literature | ||
6. | ALA1810435 | B | Inhibition of recombinant catalytic domain of TMPRSS2 expressed in Escherichia coli using Dcyclohexylalanine- Pro-Arg-AMC as substrate by fluorescence plate reader analysis | 3 | ALA1806464 | assay format | Scientific Literature | ||
7. | ALA1810436 | F | Antiviral activity against Influenza A virus (A/Hamburg/5/09 (H1N1)) virus infected in MDCK cells expressing airway trypsin-like protease HAT assessed as infected cells at 10 uM after 24 hrs by immunostaining in presence of doxycycline relative to control | Influenza A virus | 4 | ALA1806464 | organism-based format | Scientific Literature | |
8. | ALA1810491 | F | Antiviral activity against Influenza A virus (A/Aichi/2/68 (H3N2)) virus infected in MDCK cells expressing airway trypsin-like protease HAT assessed as inhibition of viral replication at 1 uM after 24 hrs by immunostaining in presence of doxycycline relative to control | Influenza A virus | 4 | ALA1806464 | organism-based format | Scientific Literature | |
9. | ALA1810492 | F | Antiviral activity against Influenza A virus (A/Memphis/14/96(H1N1)) infected in MDCK cells expressing airway trypsin-like protease HAT assessed as infected cells at 10 uM after 24 hrs by immunostaining in presence of doxycycline relative to control | Influenza A virus (A/Memphis/14/1996(H1N1)) | 4 | ALA1806464 | organism-based format | Scientific Literature | |
10. | ALA1810493 | F | Antiviral activity against Influenza A virus (A/Hamburg/5/09 (H1N1)) virus infected in MDCK cells expressing airway trypsin-like protease HAT assessed as inhibition of viral replication at 1 uM after 24 hrs by immunostaining in presence of doxycycline relative to control | Influenza A virus | 4 | ALA1806464 | organism-based format | Scientific Literature | |
11. | ALA1810494 | F | Antiviral activity against Influenza A virus (A/Memphis/14/96(H1N1)) infected in MDCK cells expressing airway trypsin-like protease HAT assessed as inhibition of viral replication at 1 uM after 24 hrs by immunostaining in presence of doxycycline relative to control | Influenza A virus (A/Memphis/14/1996(H1N1)) | 4 | ALA1806464 | organism-based format | Scientific Literature |