| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1817445 | A | Plasma concentration in DBA/2 mouse at 160 mg/kg/day, po administered for 7 days with water | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 2. | ALA1817446 | B | Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs by HPLC analysis | Mus musculus | 76 | cell-based format | Scientific Literature | ||
| 3. | ALA1817447 | F | Cytotoxicity against mouse P815B cells after 8 hrs by MTT assay | Mus musculus | 76 | cell-based format | Scientific Literature | ||
| 4. | ALA1817448 | P | Chemical stability of the compound in phosphate buffered saline assessed as compound remaining at pH 7.4 after 1.5 hrs | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA1817449 | B | Competitive inhibition of human recombinant TDO expressed in Escherichia coli BL21 using L-tryptophan as substrate by measuring conversion of N-formylkynurenine into kynurenine after 30 mins by Michaelis-Menten steady state analysis | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 6. | ALA1817450 | P | Solubility of the compound in phosphate buffered saline at pH 7.4 | 3 | small-molecule physicochemical format | Scientific Literature |
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