| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1816725 | B | Inhibition of 17Beta-HSD3 expressed in homogenized HEK293 cells assessed as transformation of [14C]-4-androstene-3,17-dione into [14C]-testosterone in presence of NADPH at 0.01 uM | 65 | cell-based format | Scientific Literature | |||
| 2. | ALA1816726 | B | Inhibition of 17Beta-HSD3 expressed in homogenized HEK293 cells assessed as transformation of [14C]-4-androstene-3,17-dione into [14C]-testosterone in presence of NADPH at 0.1 uM | 65 | cell-based format | Scientific Literature | |||
| 3. | ALA1816728 | B | Inhibition of 17Beta-HSD3 expressed in intact HEK293 cells assessed as transformation of [14C]-4-androstene-3,17-dione into [14C]-testosterone in presence of NADPH at 0.1 uM after 1 hr incubation | 65 | cell-based format | Scientific Literature | |||
| 4. | ALA1816730 | B | Activation of androgen receptor in androgen-sensitive (AR+) mouse Shionogi cells assessed as stimulation of cell proliferation after 10 days at 0.1 uM relative to control | Mus musculus | 5 | assay format | Scientific Literature | ||
| 5. | ALA1816732 | B | Activation of androgen receptor in androgen-sensitive (AR+) mouse Shionogi cells assessed as stimulation of cell proliferation after 10 days at 1 uM relative to control | Mus musculus | 4 | assay format | Scientific Literature | ||
| 6. | ALA1816733 | B | Inhibition of 17Beta-HSD3 expressed in intact HEK293 cells assessed as transformation of [14C]-4-androstene-3,17-dione into [14C]-testosterone in presence of NADPH after 1 hr incubation | 2 | cell-based format | Scientific Literature | |||
| 7. | ALA3607509 | B | Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate measured based on 18% of initial enzyme transformation at 0.1 uM after 2 hrs | Rattus norvegicus | 32 | assay format | Scientific Literature | ||
| 8. | ALA3607510 | B | Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate measured based on 18% of initial enzyme transformation at 1 uM after 2 hrs | Rattus norvegicus | 25 | assay format | Scientific Literature | ||
| 9. | ALA3607511 | B | Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate measured based on 4% of initial enzyme transformation at 1 uM after 2 hrs | Rattus norvegicus | 17 | assay format | Scientific Literature | ||
| 10. | ALA3607512 | B | Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate measured based on 4% of initial enzyme transformation at 10 uM after 2 hrs | Rattus norvegicus | 17 | assay format | Scientific Literature | ||
| 11. | ALA3607513 | F | Androgenic activity in human LAPC4 cells expressing androgen receptor assessed as induction of cell proliferation at 0.1 uM after 3 days by MTS assay relative to control | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
| 12. | ALA3607514 | F | Androgenic activity in human LAPC4 cells expressing androgen receptor assessed as induction of cell proliferation at 1 uM after 3 days by MTS assay relative to control | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
| 13. | ALA3607515 | B | Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate measured based on 33% of initial enzyme transformation at 0.1 uM after 2 hrs | Rattus norvegicus | 13 | assay format | Scientific Literature | ||
| 14. | ALA3607516 | B | Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate measured based on 33% of initial enzyme transformation at 1 uM after 2 hrs | Rattus norvegicus | 13 | assay format | Scientific Literature | ||
| 15. | ALA3607517 | B | Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate measured based on 33% of initial enzyme transformation at 10 uM after 2 hrs | Rattus norvegicus | 13 | assay format | Scientific Literature | ||
| 16. | ALA3607518 | B | Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate measured based on 18% of initial enzyme transformation at 0.01 uM after 2 hrs | Rattus norvegicus | 17 | assay format | Scientific Literature | ||
| 17. | ALA3607519 | B | Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate after 2 hrs | Rattus norvegicus | 5 | assay format | Scientific Literature | ||
| 18. | ALA3607522 | B | Inhibition of 17beta-HSD3 (unknown origin) expressed in human LNCaP cells using [14C]-4-androstene-3,17-dione as substrate at 0.5 uM after 3 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3801880 | B | Inhibition of 17betaHSD3 (unknown origin) transfected in human LNCAP cells assessed as conversion of [14C]-4-androstene-3,17-dione into [14C]-testosterone after 3 hrs | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA3801886 | B | Inhibition of 17betaHSD3 (unknown origin) transfected in HEK293 cells | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!