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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA2051194 F Hypoglycemic effect in db/db mouse assessed as reduction in glucose AUC (0 to 8 hrs) at 100 mg/kg, po administered as single dose by hexokinase method relative to untreated control Mus musculus 1 organism-based format Scientific Literature 2. ALA2051196 A Half life in db/db mouse at 10 mg/kg, po administered as single dose by LC-MS/MS system method Mus musculus 3 organism-based format Scientific Literature 3. ALA2051197 A Tmax in db/db mouse at 10 mg/kg, po administered as single dose by LC-MS/MS system method Mus musculus 3 organism-based format Scientific Literature 4. ALA2051198 A Cmax in db/db mouse at 10 mg/kg, po administered as single dose by LC-MS/MS system method Mus musculus 3 organism-based format Scientific Literature 5. ALA2051199 A AUC (infinity) in db/db mouse at 10 mg/kg, po administered as single dose by LC-MS/MS system method Mus musculus 3 organism-based format Scientific Literature 6. ALA2051200 A Apparent volume of distribution during terminal phase in db/db mouse at 10 mg/kg, po administered as single dose by LC-MS/MS system method Mus musculus 3 organism-based format Scientific Literature 7. ALA2051201 A Apparent oral clearance in db/db mouse at 10 mg/kg, po administered as single dose by LC-MS/MS system method Mus musculus 3 organism-based format Scientific Literature 8. ALA1821169 B Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins Homo sapiens 17 cell-based format Scientific Literature 9. ALA1821170 B Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins Homo sapiens 17 cell-based format Scientific Literature 10. ALA1821171 B Selectivity ratio of IC50 for human SGLT1 to IC50 for human SGLT2 Homo sapiens 17 assay format Scientific Literature 11. ALA1821172 A Cmax in db/db mouse at 10 mg/kg, po by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 12. ALA1821173 A Apparent oral clearance in db/db mouse at 10 mg/kg, po by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 13. ALA1821174 A Apparent volume of distribution during terminal phase in db/db mouse at 10 mg/kg, po by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 14. ALA1821175 A Half life in db/db mouse at 10 mg/kg, po by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 15. ALA1821176 F Antidiabetic activity in db/db mouse assessed as reduction of blood glucose level at 100 mg/kg, po after 8 hrs by hexokinase method Mus musculus 2 organism-based format Scientific Literature