# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1821182 | B | Binding affinity to recombinant C1B domain of PKCalpha expressed in Escherichia coli BL21 (DE3) after 45 mins by fluorescence quenching assay | 4 | ALA1817580 | assay format | Scientific Literature | ||
2. | ALA1821183 | B | Inhibition of TPA-induced membrane translocation of PKCalpha expressed in HEK293 cells assessed as protein found in membrane fraction at 100 uM after 2 hrs by Western blotting relative to TPA | 9 | ALA1817580 | cell-based format | Scientific Literature | ||
3. | ALA1821185 | B | Inhibition of membrane translocation of PKCalpha expressed in HEK293 cells assessed as increase of protein found in membrane fraction at 100 uM after 2 hrs by Western blotting relative to resveratrol | 8 | ALA1817580 | cell-based format | Scientific Literature | ||
4. | ALA1821186 | B | Binding affinity to recombinant C1 domain of PKCalpha expressed in Escherichia coli BL21 (DE3) after 45 mins by fluorescence quenching assay | 5 | ALA1817580 | assay format | Scientific Literature | ||
5. | ALA1821187 | A | Cytotoxicity against HEK293 cells assessed as increase in cell viability at 100 uM after 48 hrs by MTT assay relative to resveratrol | Homo sapiens | 8 | ALA1817580 | cell-based format | Scientific Literature | |
6. | ALA3056580 | F | Antioxidant activity assessed as superoxide scavenging activity in riboflavin light-NBT system | 8 | ALA3045624 | assay format | Scientific Literature | ||
7. | ALA5234968 | F | Antiviral activity against HIV-1 NL 4-3 (X4) infected in human MT4 cells assessed as inhibition of virus induced cytopathic effect by MTT assay | Human immunodeficiency virus 1 | 1 | ALA5233255 | organism-based format | Scientific Literature | |
8. | ALA5234999 | T | Cytotoxicity against human MT4 cells by MTT assay | Homo sapiens | 1 | ALA5233255 | cell-based format | Scientific Literature | |
9. | ALA5235000 | T | Selectivity index, ratio of CC50 for cytotoxicity against human MT4 cells to EC50 for antiviral activity against HIV-1 NL 4-3 (X4) infected in human MT4 cells | 1 | ALA5233255 | cell-based format | Scientific Literature | ||
10. | ALA5235001 | F | Antiviral activity against HIV-1 NL 4-3 (X4) infected in human TZM-bl cells assessed as inhibition of virus induced cytopathic effect by luciferase based assay | Human immunodeficiency virus 1 | 1 | ALA5233255 | organism-based format | Scientific Literature | |
11. | ALA5235002 | T | Cytotoxicity against human TZM-bl cells by luciferase assay | Homo sapiens | 1 | ALA5233255 | cell-based format | Scientific Literature | |
12. | ALA5235003 | T | Selectivity index, ratio of CC50 for cytotoxicity against human TZM-bl cells to EC50 for antiviral activity against HIV-1 NL 4-3 (X4) infected in human TZM-bl cells | 1 | ALA5233255 | cell-based format | Scientific Literature | ||
13. | ALA5235004 | F | Antiviral activity against HIV-1 Bal (R5) infected in human TZM-bl cells assessed as inhibition of virus induced cytopathic effect by luciferase based assay | Human immunodeficiency virus 1 | 1 | ALA5233255 | organism-based format | Scientific Literature | |
14. | ALA5235005 | T | Selectivity index, ratio of CC50 for cytotoxicity against human TZM-bl cells to EC50 for antiviral activity against HIV-1 Bal (R5) infected in human TZM-bl cells | 1 | ALA5233255 | cell-based format | Scientific Literature |