# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1827060 | F | Inhibition of hedgehog signaling pathway in mouse Shh Light2 cells by Gli-dependent reporter gene assay | Mus musculus | 38 | ALA1821583 | cell-based format | Scientific Literature | |
2. | ALA1827061 | B | Displacement of BODIPY-cyclopamine from Smo expressed in COS-1 cells after 4 to 6 hrs by Flow Cytometry analysis in presence of 2% fetal calf serum | 38 | ALA1821583 | cell-based format | Scientific Literature | ||
3. | ALA1827062 | B | Displacement of BODIPY-cyclopamine from Smo expressed in COS-1 cells after 4 to 6 hrs by Flow Cytometry analysis in presence of 20% normal human serum | 38 | ALA1821583 | cell-based format | Scientific Literature | ||
4. | ALA1827520 | F | Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay | Mus musculus | 42 | ALA1821555 | cell-based format | Scientific Literature | |
5. | ALA1827521 | B | Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | 85 | ALA1821555 | cell-based format | Scientific Literature | ||
6. | ALA1827522 | A | Intrinsic clearance in rat liver microsomes assessed per mg of protein | Rattus norvegicus | 8 | ALA1821555 | microsome format | Scientific Literature | |
7. | ALA1827524 | A | Intrinsic clearance in human liver microsomes assessed per mg of protein | Homo sapiens | 3 | ALA1821555 | microsome format | Scientific Literature | |
8. | ALA1827525 | A | Clearance in rat | Rattus norvegicus | 6 | ALA1821555 | organism-based format | Scientific Literature | |
9. | ALA1827526 | P | Lipophilicity, log D of the compound | 7 | ALA1821555 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA1827700 | A | Inhibition of human ERG | Homo sapiens | 4 | ALA1821555 | single protein format | Scientific Literature | |
11. | ALA1827704 | B | Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric analysis | 23 | ALA1821555 | cell-based format | Scientific Literature | ||
12. | ALA1827705 | A | Terminal half life in rat | Rattus norvegicus | 4 | ALA1821555 | organism-based format | Scientific Literature | |
13. | ALA1827706 | A | Clearance in dog | Canis lupus familiaris | 2 | ALA1821555 | organism-based format | Scientific Literature | |
14. | ALA1827707 | A | Half life in dog | Canis lupus familiaris | 2 | ALA1821555 | organism-based format | Scientific Literature | |
15. | ALA1827708 | A | Inhibition of cytochrome P450 at 30 uM | 2 | ALA1821555 | assay format | Scientific Literature | ||
16. | ALA1827709 | A | Induction of cytochrome P450 at 30 uM | 2 | ALA1821555 | assay format | Scientific Literature |