# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1825380 | B | Selectivity for human HCN1 over human HCN4 | Homo sapiens | 17 | ALA1821572 | assay format | Scientific Literature | |
2. | ALA1825382 | B | Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assay | Homo sapiens | 35 | ALA1821572 | cell-based format | Scientific Literature | |
3. | ALA1825383 | B | Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assay | Homo sapiens | 35 | ALA1821572 | cell-based format | Scientific Literature | |
4. | ALA1825384 | A | Half life in human liver microsomes | Homo sapiens | 2 | ALA1821572 | microsome format | Scientific Literature | |
5. | ALA1825385 | B | Inhibition of human HCN2 heterologously expressed in HEK-293 cells after 30 mins by VIPR assay | Homo sapiens | 1 | ALA1821572 | cell-based format | Scientific Literature | |
6. | ALA1825386 | B | Inhibition of human HCN3 heterologously expressed in HEK-293 cells after 30 mins by VIPR assay | Homo sapiens | 1 | ALA1821572 | cell-based format | Scientific Literature | |
7. | ALA1825387 | F | Antiallodynic activity in ip dosed C57BL/6 mouse spared-nerve injury model assessed as reduction of tactile allodynia after 60 mins | Mus musculus | 2 | ALA1821572 | organism-based format | Scientific Literature | |
8. | ALA1825388 | T | Toxicity in C57BL/6 mouse assessed as induction of bradycardia after 50 mins by ECG study | Mus musculus | 2 | ALA1821572 | organism-based format | Scientific Literature |