# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2060139 | B | Inhibition of HIF1 transcriptional activity in human LN229 cells expressing VEGF-HRE-V6R and coexpressing luciferase, lac Z gene incubated for 1 hr in normoxia condition followed by 24 hrs in hypoxia condition by reporter gene assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
2. | ALA2060140 | B | Inhibition of HIF1 transcriptional activity in human LN229 cells expressing VEGF-HRE-V6R and coexpressing lac Z gene at 10 uM incubated for 1 hr in normoxia condition followed by 24 hrs in hypoxia condition by luciferase reporter gene assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
3. | ALA2060141 | F | Downregulation of HIF1alpha protein level in human LN229 cells expressing VEGF-HRE-V6R at 10 uM incubated for 1 hr in normoxia condition followed by 24 hrs in hypoxia condition by Western blot analysis relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
4. | ALA1825507 | B | Inhibition of hypoxia-induced HIF1 activation in human LN229 cells expressing HRE-AP reporter gene assessed as HRE remaining activity at 10 uM preincubated for 1 hr under normoxia condition followed by 24 hrs incubation under hypoxia condition by alkaline phosphatase reporter assay relative to control | Homo sapiens | 47 | cell-based format | Scientific Literature | ||
5. | ALA1941974 | B | Inhibition of HIF1 in human LN229 cells after 1 hr preincubation under hypoxic condition measured after 24 hrs by luciferase reporter gene assay | Homo sapiens | 56 | cell-based format | Scientific Literature |