# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1828341 | U | Ratio of EC50 for microtubule depolymerization in human MDA-MB-435 cells to IC50 for human MDA-MB-435 cells | 4 | ALA1821698 | cell-based format | Scientific Literature | ||
2. | ALA1828342 | F | Cell cycle arrest in human MDA-MB-435 cells assessed as accumulation of cells at G2/M phase at 3 times IC50 after 18 hrs by flow cytometry | Homo sapiens | 4 | ALA1821698 | cell-based format | Scientific Literature | |
3. | ALA1828343 | F | Antiproliferative activity against human MDA-MB-435 cells by SRB assay | Homo sapiens | 4 | ALA1821698 | cell-based format | Scientific Literature | |
4. | ALA1828344 | B | Inhibition of microtubule polymerization in human MDA-MB-435 cells | Homo sapiens | 4 | ALA1821698 | cell-based format | Scientific Literature | |
5. | ALA1828345 | B | Inhibition of bovine brain tubulin assembly in A-10 cells | Bos taurus | 4 | ALA1821698 | cell-based format | Scientific Literature | |
6. | ALA1828346 | B | Displacement of [3H]colchicine from bovine brain tubulin in A-10 cells at 1 uM | Bos taurus | 4 | ALA1821698 | cell-based format | Scientific Literature | |
7. | ALA1828451 | B | Displacement of [3H]colchicine from bovine brain tubulin in A-10 cells at 5 uM | Bos taurus | 4 | ALA1821698 | cell-based format | Scientific Literature | |
8. | ALA1828452 | F | Antiproliferative activity against human SKOV3 cells | Homo sapiens | 5 | ALA1821698 | cell-based format | Scientific Literature | |
9. | ALA1828453 | F | Antiproliferative activity against MDR-1-6/6 overexpressing human SKOV3 cells | Homo sapiens | 5 | ALA1821698 | cell-based format | Scientific Literature | |
10. | ALA1828454 | F | Relative resistance ratio of IC50 for MDR-1-6/6 overexpressing human SKOV3 cells to IC50 for human SKOV3 cells | Homo sapiens | 5 | ALA1821698 | cell-based format | Scientific Literature | |
11. | ALA1828455 | F | Antiproliferative activity against human HeLa cells | Homo sapiens | 5 | ALA1821698 | cell-based format | Scientific Literature | |
12. | ALA1828456 | F | Antiproliferative activity against beta3-tubulin overexpressing human HeLa cells | Homo sapiens | 5 | ALA1821698 | cell-based format | Scientific Literature | |
13. | ALA1828457 | F | Relative resistance ratio of IC50 for beta3-tubulin overexpressing human HeLa cells to IC50 for human HeLa cells | Homo sapiens | 5 | ALA1821698 | cell-based format | Scientific Literature | |
14. | ALA1828458 | F | Cell cycle arrest in human MDA-MB-435 cells assessed as accumulation of cells at subG1 phase at 3 times IC50 after 18 hrs by flow cytometry | Homo sapiens | 3 | ALA1821698 | cell-based format | Scientific Literature | |
15. | ALA2427436 | B | Displacement of [3H]-colchicine from pig brain tubulin at 5 uM after 10 mins by scintillation counting analysis relative to control | Sus scrofa | 3 | ALA2424583 | assay format | Scientific Literature | |
16. | ALA2427437 | B | Displacement of [3H]-colchicine from pig brain tubulin at 1 uM after 10 mins by scintillation counting analysis relative to control | Sus scrofa | 3 | ALA2424583 | assay format | Scientific Literature | |
17. | ALA2427438 | B | Inhibition of pig brain tubulin assembly preincubated for 15 mins followed by GTP addition measured after 20 mins by spectrophotometric analysis in presence of glycerol | Sus scrofa | 3 | ALA2424583 | assay format | Scientific Literature | |
18. | ALA2427640 | F | Cytotoxicity against human MDA-MB-468 cells assessed as growth inhibition after 48 hrs by SRB assay | Homo sapiens | 2 | ALA2424583 | cell-based format | Scientific Literature | |
19. | ALA2427641 | F | Cytotoxicity against human Hs578T cells assessed as growth inhibition after 48 hrs by SRB assay | Homo sapiens | 2 | ALA2424583 | cell-based format | Scientific Literature | |
20. | ALA2427642 | F | Cytotoxicity against human BT549 cells assessed as growth inhibition after 48 hrs by SRB assay | Homo sapiens | 2 | ALA2424583 | cell-based format | Scientific Literature |