| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1817408 | B | Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 2. | ALA1817409 | B | Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells | Rattus norvegicus | 16 | cell-based format | Scientific Literature | ||
| 3. | ALA1817410 | P | Distribution coefficient log D of the compound at pH 7.4 | 2 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA1817418 | F | Antagonist activity at histamine H3 receptor in rat cortical membrane | Rattus norvegicus | 1 | cell membrane format | Scientific Literature | ||
| 5. | ALA1817419 | P | Dissociation constant, pKa of the compound | 2 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA1817420 | F | Antagonist activity against human histamine H3 receptor assessed as inhibition of R-alpha-methylhistamine induced [35S]GTPgammaS binding | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 7. | ALA1817421 | F | Inverse agonist activity at human histamine H3 receptor assessed as inhibition of R-alpha-methylhistamine induced [35S]GTPgammaS binding | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 8. | ALA1817422 | F | Antagonist activity against rat histamine H3 receptor assessed as inhibition of R-alpha-methylhistamine induced [35S]GTPgammaS binding | Rattus norvegicus | 3 | assay format | Scientific Literature | ||
| 9. | ALA1817423 | F | Inverse agonist activity at rat histamine H3 receptor assessed as inhibition of R-alpha-methylhistamine induced [35S]GTPgammaS binding | Rattus norvegicus | 3 | assay format | Scientific Literature | ||
| 10. | ALA1817424 | B | Selectivity for human histamine H3 receptor over human H1 receptor | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA1817425 | B | Selectivity for human histamine H3 receptor over human H2 receptor | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA1817426 | B | Selectivity for human histamine H3 receptor over human H4 receptor | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA1817427 | B | Inhibition of human histamine H1 receptor at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA1817428 | B | Inhibition of human histamine H2 receptor at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA1817429 | B | Inhibition of human histamine H4 receptor at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA1817430 | B | Inhibition of muscarinic M2 receptor | 1 | single protein format | Scientific Literature | |||
| 17. | ALA1817431 | B | Inhibition of adrenergic alpha 1A receptor | 1 | single protein format | Scientific Literature | |||
| 18. | ALA1817432 | B | Inhibition of dopamine transporter | 1 | single protein format | Scientific Literature | |||
| 19. | ALA1817433 | B | Inhibition of norepinephrine transporter | 1 | single protein format | Scientific Literature | |||
| 20. | ALA1817434 | B | Inhibition of PDE3 | 1 | assay format | Scientific Literature |
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