# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1831796 | B | Inhibition of human 11 beta-HSD1 expressed in CHO cells assessed as conversion of [3H]cortisone to [3H]cortisol after 1 hr by scintillation proximity assay | Homo sapiens | 46 | ALA1828622 | cell-based format | Scientific Literature | |
2. | ALA1831797 | B | Inhibition of 11 beta-HSD1 in differentiated human adipocytes assessed as conversion of [3H]-cortisone to [3H]-cortisol after 10 mins by HPLC | Homo sapiens | 34 | ALA1828622 | cell-based format | Scientific Literature | |
3. | ALA1831905 | A | AUC (infinity) in rat at 10 mg/kg, po | Rattus norvegicus | 6 | ALA1828622 | organism-based format | Scientific Literature | |
4. | ALA1831908 | A | Half life in rat at 10 mg/kg, po | Rattus norvegicus | 6 | ALA1828622 | organism-based format | Scientific Literature | |
5. | ALA1831911 | A | Clearance in rat plasma at 2 mg/kg, iv | Rattus norvegicus | 6 | ALA1828622 | organism-based format | Scientific Literature | |
6. | ALA1832378 | A | Oral bioavailability in rat at 10 mg/kg | Rattus norvegicus | 6 | ALA1828622 | organism-based format | Scientific Literature | |
7. | ALA5245459 | B | Inhibition of human 11beta-HSD1 incubated for 22 hrs by HTRF assay | Homo sapiens | 3 | ALA5244232 | single protein format | Scientific Literature |