| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1831796 | B | Inhibition of human 11 beta-HSD1 expressed in CHO cells assessed as conversion of [3H]cortisone to [3H]cortisol after 1 hr by scintillation proximity assay | Homo sapiens | 46 | ALA1828622 | cell-based format | Scientific Literature | |
| 2. | ALA1831797 | B | Inhibition of 11 beta-HSD1 in differentiated human adipocytes assessed as conversion of [3H]-cortisone to [3H]-cortisol after 10 mins by HPLC | Homo sapiens | 34 | ALA1828622 | cell-based format | Scientific Literature | |
| 3. | ALA1831798 | B | Inhibition of human 11 beta-HSD1 expressed in CHO cells assessed as conversion of [3H]-cortisone to [3H]-cortisol after 1 hr by scintillation proximity assay in presence of human plasma | Homo sapiens | 19 | ALA1828622 | cell-based format | Scientific Literature | |
| 4. | ALA1831799 | A | Inhibition of human CYP3A4 assessed as rate of [14C]-formaldehyde/formic acid production by liquid scintillation counting | Homo sapiens | 20 | ALA1828622 | single protein format | Scientific Literature | |
| 5. | ALA1831800 | A | Metabolic stability in rat liver microsomes assessed as half life | Rattus norvegicus | 17 | ALA1828622 | microsome format | Scientific Literature | |
| 6. | ALA1831801 | B | Inhibition of human 11 beta-HSD2 expressed in CHO cells assessed as conversion of [3H]cortisol to [3H]cortisone after 1 hr by HPLC | Homo sapiens | 1 | ALA1828622 | cell-based format | Scientific Literature | |
| 7. | ALA1831802 | B | Inhibition of 17beta-HSD1 | 1 | ALA1828622 | single protein format | Scientific Literature | ||
| 8. | ALA1831803 | B | Inhibition of 3 beta-HSD2 | 1 | ALA1828622 | single protein format | Scientific Literature | ||
| 9. | ALA1831804 | B | Selectivity ratio of IC50 for human 11beta-HSD2 to IC50 for human 11beta-HSD1 | Homo sapiens | 1 | ALA1828622 | assay format | Scientific Literature | |
| 10. | ALA1831805 | A | Inhibition of CYP2D6 | 1 | ALA1828622 | single protein format | Scientific Literature | ||
| 11. | ALA1831806 | A | Inhibition of CYP2C9 | 1 | ALA1828622 | single protein format | Scientific Literature | ||
| 12. | ALA1831807 | B | Inhibition of human ERG | Homo sapiens | 1 | ALA1828622 | single protein format | Scientific Literature | |
| 13. | ALA1831808 | B | Binding affinity to FXR | 1 | ALA1828622 | single protein format | Scientific Literature | ||
| 14. | ALA1831809 | B | Binding affinity to GR | 1 | ALA1828622 | single protein format | Scientific Literature | ||
| 15. | ALA1831904 | B | Binding affinity to MR | 1 | ALA1828622 | single protein format | Scientific Literature | ||
| 16. | ALA1831905 | A | AUC (infinity) in rat at 10 mg/kg, po | Rattus norvegicus | 6 | ALA1828622 | organism-based format | Scientific Literature | |
| 17. | ALA1831906 | A | AUC (infinity) in dog at 2 mg/kg, po | Canis lupus familiaris | 1 | ALA1828622 | organism-based format | Scientific Literature | |
| 18. | ALA1831907 | A | AUC (infinity) in cynomolgus monkey at 2 mg/kg, po | Macaca fascicularis | 1 | ALA1828622 | organism-based format | Scientific Literature | |
| 19. | ALA1831908 | A | Half life in rat at 10 mg/kg, po | Rattus norvegicus | 6 | ALA1828622 | organism-based format | Scientific Literature | |
| 20. | ALA1831909 | A | Half life in dog at 2 mg/kg, po | Canis lupus familiaris | 1 | ALA1828622 | organism-based format | Scientific Literature |
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