# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1832655 | B | Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysis | Mus musculus | 16 | ALA1828629 | single protein format | Scientific Literature | |
2. | ALA1832656 | B | Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assay | 10 | ALA1828629 | single protein format | Scientific Literature | ||
3. | ALA1832657 | F | Cytotoxicity against human MDA468 cells after 72 hrs by MTS assay | Homo sapiens | 3 | ALA1828629 | cell-based format | Scientific Literature | |
4. | ALA1832658 | F | Cytotoxicity against human DU145 cells after 72 hrs by MTS assay | Homo sapiens | 3 | ALA1828629 | cell-based format | Scientific Literature | |
5. | ALA1832659 | F | Cytotoxicity against human JJN-3 cells after 72 hrs by MTS assay | Homo sapiens | 3 | ALA1828629 | cell-based format | Scientific Literature | |
6. | ALA1832660 | P | Lipophilicity, log P of the compound | 2 | ALA1828629 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA1832661 | P | Solubility of the compound in water | 2 | ALA1828629 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA3226160 | B | Competitive inhibition of human GST-tagged PTP1B catalytic domain assessed as rate of DiFMUP hydrolysis by lineweaver-burk plot analysis | Homo sapiens | 2 | ALA3217656 | single protein format | Scientific Literature | |
9. | ALA3226167 | A | Cytotoxicity against Chinese hamster CHO cells overexpressing IR assessed as cell proliferation rate at 50 uM by xCELLigence system | Cricetulus griseus | 1 | ALA3217656 | cell-based format | Scientific Literature | |
10. | ALA3226168 | A | Cytotoxicity against Chinese hamster CHO cells overexpressing IR assessed as cell proliferation rate at 0.4 to 10 uM by xCELLigence system | Cricetulus griseus | 3 | ALA3217656 | cell-based format | Scientific Literature | |
11. | ALA3226169 | B | Inhibition of PTP1B in Chinese hamster CHO cells overexpressing IR assessed as insulin-stimulated IR phosphorylation treated for 3 hrs prior to insulin stimulation for 15 mins by western blot analysis | Cricetulus griseus | 3 | ALA3217656 | cell-based format | Scientific Literature | |
12. | ALA3226170 | B | Inhibition of human GST-tagged PTP-LAR D1D2 domain assessed as DiFMUP hydrolysis by fluorometric kinetic-based assay | Homo sapiens | 3 | ALA3217656 | single protein format | Scientific Literature | |
13. | ALA3226171 | B | Inhibition of papaya papain assessed as Z-Phe-Arg-pNA hydrolysis by fluorometric kinetic-based assay | Carica papaya | 6 | ALA3217656 | single protein format | Scientific Literature | |
14. | ALA3226172 | B | Inhibition of human GST-tagged full length MKPX assessed as DiFMUP hydrolysis by fluorometric kinetic-based assay | Homo sapiens | 6 | ALA3217656 | single protein format | Scientific Literature | |
15. | ALA3226173 | B | Inhibition of human GST-tagged PRL2 A/S active mutant assessed as DiFMUP hydrolysis by fluorometric kinetic-based assay | Homo sapiens | 6 | ALA3217656 | assay format | Scientific Literature | |
16. | ALA3226174 | B | Inhibition of human GST-tagged TC-PTP catalytic domain assessed as DiFMUP hydrolysis by fluorometric kinetic-based assay | Homo sapiens | 6 | ALA3217656 | single protein format | Scientific Literature | |
17. | ALA3226175 | B | Inhibition of human GST-tagged PTP-sigma D1D2 domain assessed as DiFMUP hydrolysis by fluorometric kinetic-based assay | Homo sapiens | 6 | ALA3217656 | single protein format | Scientific Literature | |
18. | ALA3226176 | B | Inhibition of human GST-tagged PTP1B catalytic domain assessed as DiFMUP hydrolysis by fluorometric kinetic-based assay | Homo sapiens | 6 | ALA3217656 | single protein format | Scientific Literature | |
19. | ALA3226177 | B | Inhibition of papaya papain assessed as Z-Phe-Arg-pNA hydrolysis at 10 uM by fluorometric kinetic-based assay | Carica papaya | 6 | ALA3217656 | single protein format | Scientific Literature | |
20. | ALA3226178 | B | Inhibition of human GST-tagged full length MKPX assessed as DiFMUP hydrolysis at 10 uM by fluorometric kinetic-based assay | Homo sapiens | 6 | ALA3217656 | single protein format | Scientific Literature |