# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1833183 | Functional | Antiparasitic activity against Fasciola hepatica infected in rat assessed as reduction in worm burden at 50 mg/kg, po administered as single dose measured after 6 days post treatment | Fasciola hepatica | 7 | ALA1828617 | organism-based format | Scientific Literature | |
2. | ALA1833472 | Functional | Antiparasitic activity against Fasciola hepatica infected in rat assessed as reduction in worm burden at 100 mg/kg, po administered as single dose measured after 6 days post treatment | Fasciola hepatica | 16 | ALA1828617 | organism-based format | Scientific Literature | |
3. | ALA1833473 | Functional | Antiparasitic activity against Fasciola hepatica infected in rat assessed as cure rate at 100 mg/kg, po administered as single dose measured after 6 days post treatment | Fasciola hepatica | 12 | ALA1828617 | organism-based format | Scientific Literature | |
4. | ALA3999840 | Functional | Antiproliferative activity against human A549 cells harboring wild type EGFR after 48 hrs by MTT assay | Homo sapiens | 11 | ALA3997839 | cell-based format | Scientific Literature | |
5. | ALA3999841 | Functional | Antiproliferative activity against EGFR over-expressing human A431 cells after 48 hrs by MTT assay | Homo sapiens | 11 | ALA3997839 | cell-based format | Scientific Literature | |
6. | ALA3999842 | Functional | Antiproliferative activity against human NCI-H1975 cells harboring EGFR L858R/T790M double mutant after 48 hrs by MTT assay | Homo sapiens | 11 | ALA3997839 | cell-based format | Scientific Literature | |
7. | ALA3999843 | Functional | Antiproliferative activity against human HCC827 cells harboring EGFR E746_A750 deletion mutant after 48 hrs by MTT assay | Homo sapiens | 11 | ALA3997839 | cell-based format | Scientific Literature | |
8. | ALA3999844 | ADME | Antiproliferative activity against human HL7702 cells after 48 hrs by MTT assay | Homo sapiens | 11 | ALA3997839 | cell-based format | Scientific Literature | |
9. | ALA3999845 | Binding | Inhibition of recombinant human GST-tagged EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression system by Z'-Lyte assay | Homo sapiens | 11 | ALA3997839 | assay format | Scientific Literature | |
10. | ALA3999846 | Binding | Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain (695-end residues) expressed in insect cells by Z'-Lyte assay | Homo sapiens | 11 | ALA3997839 | cell-based format | Scientific Literature | |
11. | ALA3999847 | Binding | Inhibition of recombinant human GST-tagged EGFR L858R/T790M double mutant cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression system by Z'-Lyte assay | Homo sapiens | 10 | ALA3997839 | assay format | Scientific Literature |