# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1832567 | B | Inhibition of Plasmodium falciparum IspC | Plasmodium falciparum | 8 | assay format | Scientific Literature | ||
2. | ALA1832568 | B | Inhibition of Escherichia coli IspC | Escherichia coli | 8 | assay format | Scientific Literature | ||
3. | ALA1832569 | B | Ratio of IC50 for Escherichia coli IspC to IC50 for Plasmodium falciparum IspC | 8 | assay format | Scientific Literature | |||
4. | ALA1832570 | F | Antimicrobial activity against chloroquine-resistant Plasmodium falciparum K1 infected in human erythrocytes assessed as inhibition of parasite replication | Plasmodium falciparum | 8 | organism-based format | Scientific Literature | ||
5. | ALA1832571 | A | Cytotoxicity against human MRC5 cells | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
6. | ALA1832854 | F | Antimalarial activity against Plasmodium berghei ANKA infected in Swiss mouse assessed as suppression of infected RBC at 40 mg/kg, ip bid for 5 days coadministered with ritonavir 10 mg/kg, po | Plasmodium berghei | 3 | organism-based format | Scientific Literature | ||
7. | ALA1832855 | F | Antimalarial activity against Plasmodium berghei ANKA infected in Swiss mouse assessed as survival at 40 mg/kg, ip bid for 5 days coadministered with ritonavir 40 mg/kg, po | Plasmodium berghei | 3 | organism-based format | Scientific Literature | ||
8. | ALA2167524 | F | Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum 3D7 incubated for 3 days by HRP2 detection based ELISA method | Plasmodium falciparum | 18 | organism-based format | Scientific Literature | ||
9. | ALA2167525 | F | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum Dd2 incubated for 3 days by HRP2 detection based ELISA method | Plasmodium falciparum | 18 | organism-based format | Scientific Literature | ||
10. | ALA2434041 | F | Antimicrobial activity against chloroquine-resistant blood stage forms of Plasmodium falciparum Dd2 after 3 days by HRP2-based ELISA | Plasmodium falciparum | 22 | organism-based format | Scientific Literature | ||
11. | ALA2434042 | F | Antimicrobial activity against chloroquine-sensitive blood stage forms of Plasmodium falciparum 3D7 after 3 days by HRP2-based ELISA | Plasmodium falciparum | 22 | organism-based format | Scientific Literature | ||
12. | ALA2434043 | B | Inhibition of Plasmodium falciparum IspC expressed in recombinant Escherichia coli M15 by photometric assay | Plasmodium falciparum | 24 | assay format | Scientific Literature | ||
13. | ALA2434044 | B | Inhibition of Mycobacterium tuberculosis IspC by photometric assay | Mycobacterium tuberculosis | 25 | single protein format | Scientific Literature | ||
14. | ALA2434045 | B | Inhibition of Escherichia coli IspC by photometric assay | Escherichia coli | 25 | assay format | Scientific Literature | ||
15. | ALA3411605 | B | Inhibition of recombinant Plasmodium falciparum IspC using [3,4,5-13C3]1-Deoxy-D-xylulose 5-phosphate substrate by photometric assay | Plasmodium falciparum | 25 | assay format | Scientific Literature | ||
16. | ALA3411606 | F | Antiplasmodial activity against blood stage forms of multidrug-resistant Plasmodium falciparum Dd2 incubated for 3 days by HRP2 detection based ELISA method | Plasmodium falciparum | 25 | organism-based format | Scientific Literature | ||
17. | ALA3411607 | F | Antiplasmodial activity against blood stage forms of chloroquine-sensitive Plasmodium falciparum 3D7 incubated for 3 days by HRP2 detection based ELISA method | Plasmodium falciparum | 25 | organism-based format | Scientific Literature | ||
18. | ALA3411608 | F | Antiplasmodial activity against blood stage forms of chloroquine-sensitive Plasmodium falciparum D10 incubated for 3 days by HRP2 detection based ELISA method | Plasmodium falciparum | 25 | organism-based format | Scientific Literature | ||
19. | ALA3411656 | A | Cytotoxicity against human HeLa cells | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
20. | ALA3411657 | T | Selectivity index, ratio of IC50 for human HeLa cells to IC50 for blood stage forms of multidrug-resistant Plasmodium falciparum Dd2 | 12 | cell-based format | Scientific Literature |