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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA1838945 F Antitumor activity against human IGROV1 cells expressing human RFC, FRalpha and PCFT xenografted in SCID mouse assessed as tumor growth inhibition at 40 mg/kg, iv administered on days 3, 7, 11, 15, and 19 postimplantation Homo sapiens 1 ALA1833876 organism-based format Scientific Literature 2. ALA1838946 F Antiproliferative activity against chinese hamster PC43-10 expressing human RFC assessed as reduction of viable cells after 96 hrs Cricetulus griseus 9 ALA1833876 assay format Scientific Literature 3. ALA1838947 A Antiproliferative activity against chinese hamster R2 cells assessed as reduction of viable cells after 96 hrs Cricetulus griseus 9 ALA1833876 cell-based format Scientific Literature 4. ALA1838948 F Antiproliferative activity against chinese hamster RT16 cells expressing human FRalpha assessed as reduction of viable cells after 96 hrs Cricetulus griseus 9 ALA1833876 cell-based format Scientific Literature 5. ALA1838949 F Antiproliferative activity against chinese hamster RT16 cells expressing human FRalpha assessed as reduction of viable cells after 96 hrs in the presence of 200 nM folic acid Cricetulus griseus 9 ALA1833876 cell-based format Scientific Literature 6. ALA1838950 F Antiproliferative activity against chinese hamster D4 cells expressing human FRbeta assessed as reduction of viable cells after 96 hrs Cricetulus griseus 9 ALA1833876 cell-based format Scientific Literature 7. ALA1838951 F Antiproliferative activity against chinese hamster D4 cells expressing human FRbeta assessed as reduction of viable cells after 96 hrs in the presence of 200 nM folic acid Cricetulus griseus 9 ALA1833876 cell-based format Scientific Literature 8. ALA1838952 F Antiproliferative activity against chinese hamster R2 cells expressing human PCFT assessed as reduction of viable cells after 96 hrs Cricetulus griseus 9 ALA1833876 cell-based format Scientific Literature 9. ALA1838953 A Antiproliferative activity against chinese hamster R2(VC) cells expressing human PCFT assessed as reduction of viable cells after 96 hrs Cricetulus griseus 9 ALA1833876 assay format Scientific Literature 10. ALA1838954 F Antiproliferative activity against human KB cells expressing human RFC, FRalpha and PCFT assessed as reduction of viable cells after 96 hrs Homo sapiens 9 ALA1833876 cell-based format Scientific Literature 11. ALA1838955 F Antiproliferative activity against human KB cells expressing human RFC, FRalpha and PCFT assessed as reduction of viable cells after 96 hrs in the presence of 200 nM folic acid Homo sapiens 9 ALA1833876 cell-based format Scientific Literature 12. ALA1838956 F Antiproliferative activity against human IGROV1 cells expressing human RFC, FRalpha and PCFT assessed as reduction of viable cells after 96 hrs Homo sapiens 9 ALA1833876 cell-based format Scientific Literature 13. ALA1838957 F Antiproliferative activity against human IGROV1 cells expressing human RFC, FRalpha and PCFT assessed as reduction of viable cells after 96 hrs in the presence of 200 nM folic acid Homo sapiens 9 ALA1833876 cell-based format Scientific Literature 14. ALA1838958 F Ratio of IC50 for chinese hamster RT16 cells expressing FRalpha cells to IC50 for chinese hamster D4 cells expressing human FRbeta Cricetulus griseus 2 ALA1833876 cell-based format Scientific Literature 15. ALA1838959 F Antiproliferative activity against chinese hamster R2 cells expressing human PCFT assessed as inhibition of colony formation after 10 to 14 days Cricetulus griseus 4 ALA1833876 cell-based format Scientific Literature 16. ALA1839674 B Inhibition of human RFC-mediated [3H]MTX uptake in chinese hamster PC43-10 cells at 10 uM after 2 mins relative to control Homo sapiens 8 ALA1833876 cell-based format Scientific Literature 17. ALA1837097 B Induction of current in human PCFT expressed in xenopus oocyte at 5 uM at holding potential -90 mV by voltage clamp assay Homo sapiens 3 ALA1833876 assay format Scientific Literature 18. ALA1837098 B Inhibition of human PCFT-mediated [3H]MTX uptake ectopically expressed in chinese hamster R2 cells at 10 uM at pH 5.5 to 7.2 Homo sapiens 4 ALA1833876 cell-based format Scientific Literature 19. ALA1837099 B Inhibition of human PCFT-mediated [3H]MTX uptake expressed in chinese hamster R2 cells at pH 5.5 by dixon plot analysis Homo sapiens 1 ALA1833876 cell-based format Scientific Literature 20. ALA1837100 B Inhibition of human PCFT-mediated [3H]MTX uptake expressed in chinese hamster R2 cells at pH 6.8 by dixon plot analysis Homo sapiens 1 ALA1833876 cell-based format Scientific Literature